George Washington University

This study looks at whether a 6-month lifestyle program or the medication metformin is better for helping mothers lose weight after having a baby and dealing with gestational diabetes. About 60 women who gave birth in the last 3 to 12 months and have a BMI between 25 and 45 will …

This study tests whether sending text messages can help homeless adults with poorly controlled diabetes improve their blood sugar levels. About 100 participants will receive SMS reminders and tips. The goal is to see if this simple approach helps them stick to medications and doc…

This study tests an oral drug called glycerol tributyrate in 24 adults with MELAS or LHON-Plus, two rare genetic diseases that affect energy production in cells. The goal is to see if the drug is safe and can improve energy metabolism. Each participant serves as their own control…

This study tests a program called HAVEN=CONNECT, designed to prevent suicide and depression in Black youth aged 13-19. The program is delivered through predominantly Black churches and includes training for church leaders and a youth support component. Researchers will measure ch…

This study tests whether community-led programs can prevent intimate partner violence in Malawi. About 1,700 women in food-insecure households will take part. The approach combines community mobilization with women's economic empowerment to address root causes of violence.

This study looks at whether avoiding non-nutritive sweeteners (like those in diet sodas) during pregnancy and breastfeeding can help prevent obesity in babies and improve blood sugar control in moms. About 324 pregnant women who regularly consume these sweeteners will be assigned…

This study tests a community program that helps teenagers in Washington Highlands imagine and pursue life paths that don't involve violence. The goal is to prevent firearm violence by offering real opportunities and support. About 1000 youth and their parents will take part, and …

This study tests whether a community program called SASA! Together can reduce intimate partner violence in Malawi. About 4,800 women and men aged 18-49 who have been in a romantic relationship will take part. The program works by changing harmful social norms and empowering the w…

This study tests whether taking CoQ10 and glutathione before and after heart surgery can prevent acute kidney injury. About 242 adults having elective bypass surgery will receive either the supplements or a placebo. The goal is to see if these mitochondrial-supporting nutrients r…

This study tests whether a special nerve block injection given before lung surgery can lower pain and the amount of pain medicine patients need afterward. About 70 adults having lung tumor removal will take part. Researchers will track pain scores and medication use for 24 hours …

This study tests whether a single injection of long-lasting pain medicine (Exparel) works as well as a continuous drip of pain medicine through small tubes (catheters) for people having surgery after a broken leg, ankle, or thigh bone. About 90 patients will be enrolled, and thei…

This study looks at whether starting daily activities early after a wrist fracture (while in a cast) helps people recover better. About 64 adults with a broken wrist will be split into two groups: one gets tips on doing daily tasks safely, the other only gets standard cast care. …

This study compares two types of nerve blocks—erector spinae and intercostal—for controlling pain after lung surgery. About 120 adults having video-assisted lung procedures will receive one of the two blocks. Researchers will measure pain scores and pain medication use for up to …

This study follows 3,600 overweight or obese teenagers who are at high risk for developing type 2 diabetes. Researchers will track changes in blood sugar, insulin, and other factors over time to learn how the disease starts. The goal is to find early warning signs and better unde…

This study tests a program to help people make their homes smoke-free in Armenia and Georgia, where many men smoke but few homes have rules against indoor smoking. The goal is to reduce secondhand smoke exposure for children and non-smokers. Researchers will work with local partn…

This study aims to see if giving healthy adults a small number of whipworm eggs is safe and can cause a mild, controlled infection. Researchers will test different doses in 18 volunteers aged 18-45 to find the best dose that is safe and leads to a consistent infection. The goal i…

This study looks at whether putting a warning label on foods with non-sugar sweeteners (like diet sodas) helps Brazilian parents choose healthier options for their children. About 1,068 parents will pick foods for their kids in an online shopping game, with some seeing no label, …

This study aims to see if community-based mental health services can improve depression, anxiety, and PTSD. About 1,000 adults with mild to moderate psychological distress will receive these services and be tracked over time. The goal is to learn what works best to support mental…

This study follows up to 19,000 people with HIV or at high risk for HIV in Washington, DC, to see how well treatments and prevention services work over time. Researchers will track viral suppression rates and new infections to improve care across the city. Participants are from t…

This study is for people with early-stage breast cancer (Stage I-III) who will receive hormone therapy before surgery. The goal is to see how the cancer responds to this therapy and to find ways to predict that response. Participants will take hormone therapy as part of their reg…