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A fiber supplement may help perimenopausal women — a trial puts it to the test

NCT ID NCT07724522

Recruiting now Disease control Sponsor: George Washington University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether taking inulin, a type of dietary fiber, for two weeks can improve cardiovascular health, muscle function, and the balance of gut and vaginal bacteria in perimenopausal women who are overweight or have obesity. Participants will take either inulin or a placebo for two weeks, then switch after a washout period. The study aims to see if this simple supplement can ease some health risks that rise during the menopause transition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
inulin, a dietary fiber supplement
What this could lead to
If it works, this could point toward a simple dietary supplement to help manage cardiometabolic risks during the perimenopausal transition.
What could go wrong
This is a small, early-stage trial with only 27 participants and a short 2-week treatment period, so results may not apply broadly. Inulin can cause digestive discomfort in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Insulin Resistance Obesity obesity disorder Overweight skeletal muscle disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES (CVD) DIETARY FIBER GASTROINTESTINAL MICROBIOME INSULIN RESISTANCE INULIN MICROBIOTA MUSCLE, SKELETAL OBESITY & OVERWEIGHT PERIMENOPAUSAL WOMEN PREBIOTICS VASCULAR HEALTH WOMEN HEALTH

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Milken Institute School of Public Health

    RECRUITING

    Washington D.C., District of Columbia, 20052, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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