GASTROINTESTINAL MICROBIOME

This trial tests whether taking inulin, a type of dietary fiber, for two weeks can improve cardiovascular health, muscle function, and the balance of gut and vaginal bacteria in perimenopausal women who are overweight or have obesity. Participants will take either inulin or a pla…

This study tests whether a 20-day fasting schedule before hip replacement surgery can reduce complications like infections. 130 adults will either follow the fasting plan or receive standard care. Researchers will measure changes in gut bacteria and immune markers to see if fasti…

This study looks at whether drinking instant coffee every day for 6 weeks can reduce liver fat and improve gut health in people who have finished treatment for stage I-III colorectal cancer. About 80 adults who completed surgery, chemo, or radiation at least 2 months ago will par…

This study tests whether a nutritional supplement called AG1 can help fill nutrient gaps and improve gut health in 120 adults taking GLP-1 medications like Ozempic or Wegovy. Participants will take either the supplement or a placebo for a period, and researchers will measure chan…

This study tests whether following a Mediterranean-style diet for 18 months is practical and beneficial for people with Parkinson's disease. Researchers will see if the diet is easy to stick with and if it leads to changes in gut bacteria or Parkinson's symptoms. About 40 partici…

This study investigates whether the diversity of gut bacteria is linked to liver and kidney injury in people with sepsis. Researchers will collect stool and blood samples from 200 sepsis patients in intensive care and compare them with samples from healthy volunteers. By analyzin…

This study tests whether drinking plant-based beverages for two weeks can positively change the mix of bacteria in the gut. Healthy adults aged 18 to 65 will have their gut microbiome analyzed before and after consuming the drinks. The goal is to see if these beverages boost micr…

This study tests a wearable smart underwear device that measures hydrogen sulfide gas from gut microbes. 25 healthy adults will eat high-cysteine and low-cysteine diets to see if the device can detect diet-related changes in gas production. The goal is to develop a non-invasive t…

This study looks at how sleep problems affect people with ulcerative colitis, a type of inflammatory bowel disease. Researchers will study 152 participants to see how sleep quality relates to gut bacteria, nerve function, and disease activity. The goal is to understand the connec…