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Gut microbes may hold clues to sepsis organ injury

NCT ID NCT07735182

Recruiting now Knowledge-focused Sponsor: First Affiliated Hospital of Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study investigates whether the diversity of gut bacteria is linked to liver and kidney injury in people with sepsis. Researchers will collect stool and blood samples from 200 sepsis patients in intensive care and compare them with samples from healthy volunteers. By analyzing gut microbes and blood markers, they hope to uncover biological pathways that could lead to better prediction or treatment of organ damage during sepsis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If links are found, it could point toward new ways to predict or prevent organ damage in sepsis by targeting the gut microbiome.
What could go wrong
This is an observational study, not a treatment trial. It can only show associations, not cause and effect, and results may not lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY DUE TO SEPSIS GASTROINTESTINAL MICROBIOME INTENSIVE CARE MEDICINE SEPSIS SEPSIS-ASSOCIATED LIVER INJURY

Contacts and locations

Locations

  • First Affiliated hospital of zhejiang university school of medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

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