Heart surgery patients may avoid kidney damage with common supplements

NCT ID NCT06620523

Recruiting now Prevention Sponsor: George Washington University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking CoQ10 and glutathione before and after heart surgery can prevent acute kidney injury, a common complication. 242 adults scheduled for elective heart surgery will receive either the supplements or a placebo. The goal is to see if these mitochondrial-targeting supplements reduce kidney damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Coenzyme Q10 (CoQ10) and Glutathione
What this could lead to: If it works, this could point toward a simple, low-cost way to prevent kidney damage after heart surgery.
What could go wrong: This is a Phase 2 trial with only 242 participants, so results may not apply to everyone. The supplements may not reduce kidney injury more than a placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder kidney failure acute kidney injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE RENAL FAILURE SURGERY SURGERY COMPLICATIONS

Contacts and locations

Locations

George Washington University Hospital
RECRUITING

Washington D.C., District of Columbia, 20037, United States

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