Fondazione Policlinico Universitario Agostino Gemelli Irccs
Clinical trials sponsored by Fondazione Policlinico Universitario Agostino Gemelli Irccs, explained in plain language.
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Italian study tracks survival boost for Tough-to-Treat colon cancer
Disease control OngoingThis study is observing how well a specific combination of cancer drugs works for people with advanced colorectal cancer that has spread. It will follow about 300 patients across 15 Italian hospitals to see how long they live and how the treatment affects their cancer progression…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for stubborn seizures? Real-World trial tests promising drug
Disease control ENROLLING_BY_INVITATIONThis study is testing whether a medication called cenobamate can help control seizures in adults with autoimmune epilepsy, a condition where the body's immune system attacks the brain and causes seizures that are often hard to treat. Researchers will follow 30 participants for 24…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New blood test could replace liver biopsies for silent liver disease
Diagnosis OngoingThis study aims to see if a new blood test can accurately diagnose and track a serious liver disease called NASH, which is linked to obesity and type 2 diabetes. Researchers will test the blood of 828 people to see if measuring two specific markers (PLIN2 and RAB14) in white bloo…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Apr 01, 2026 21:56 UTC
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New nerve block aims to cut pain and opioid use after lung surgery
Symptom relief OngoingThis study is testing which of two nerve-blocking techniques works better for pain control after a specific type of minimally invasive lung surgery. It involves 28 adults having lung tumor removal. Researchers will compare a newer nerve block (SPSIP) to a standard one (ICN) to se…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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New surgical pouch aims to ease life after stomach removal
Symptom relief OngoingThis study is testing a new surgical technique for patients who need their entire stomach removed due to cancer. The method creates a small pouch from intestine to help reduce common side effects like rapid food dumping and poor nutrition. Researchers want to see if this approach…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Mar 27, 2026 12:37 UTC
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AI camera watches your heart and mood from afar
Knowledge-focused OngoingThis study is testing a new AI-powered camera system called HERO that can measure vital signs like heart rate and breathing, as well as detect body posture and emotional states, all without touching the patient. It involves 100 adults and aims to see how well the camera's measure…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Heart imaging study seeks to improve stent results for thousands
Knowledge-focused OngoingThis large observational study aims to understand if using a special high-resolution imaging camera (called OCT) during heart stent procedures helps doctors make better decisions and leads to better long-term outcomes. It will follow 3,200 patients who had this imaging during the…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Researchers adapt tool to gauge how IPF patients manage their health
Knowledge-focused OngoingThis study aims to adapt a questionnaire originally made for COPD patients so it can be used to measure self-care in people with idiopathic pulmonary fibrosis (IPF). Researchers will ask 156 adult IPF patients to complete the questionnaire in a single visit. The goal is to create…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists probe Body's hidden defense against dengue
Knowledge-focused OngoingThis study aims to understand how the body's T-cells respond to a new dengue vaccine called TAK-003. Researchers will enroll 30 healthy adults to analyze their immune system's reaction after vaccination. The goal is to identify markers that show if the body is protected against t…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists test remote brain checkups for dementia patients
Knowledge-focused OngoingThis study aims to validate a set of remote cognitive tests for people with dementia. Researchers are comparing how well computer-based assessments work versus traditional in-person evaluations. The goal is to create reliable tools that doctors can use to monitor brain function r…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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One-Day snapshot reveals hidden suffering in hospitals and care homes
Knowledge-focused OngoingThis study aims to understand how many people in hospitals and long-term care facilities have unmet palliative care needs. On a single day, researchers will survey 3,000 adult patients and residents about their symptoms, pain, and overall health. The goal is to gather data to imp…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Scientists map muscle loss to build better braces for rare disease
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to better understand how a genetic muscle-wasting disease, FSHD, affects movement and posture. Researchers will use MRI scans and 3D motion capture to analyze muscle damage and walking patterns in 40 adult patients. The goal is to link these detailed pictures of m…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC