Fondazione Policlinico Universitario Agostino Gemelli Irccs
Clinical trials sponsored by Fondazione Policlinico Universitario Agostino Gemelli Irccs, explained in plain language.
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Computer-Guided thin implants tested for smile gaps
Disease control CompletedThis study tested a simpler approach for replacing a single missing tooth in a visible area of the mouth. Researchers used thin dental implants placed with computer guidance in 17 patients who had narrow jawbones or small spaces. The goal was to see if this method could avoid mor…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Apr 01, 2026 21:56 UTC
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Psoriasis patients choose their favorite treatment in Head-to-Head comparison
Disease control CompletedThis study asked 30 people with mild-to-moderate psoriasis which topical treatment they preferred: Wynzora cream or Enstilar foam. Participants had previously used the foam and then switched to the cream for four weeks. Researchers measured which treatment patients liked better, …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Doctors test new monitor to protect brain during surgery
Disease control CompletedThis study tested whether using a special monitor to predict and prevent low blood pressure during major abdominal surgery helps keep the brain's oxygen levels stable. Researchers compared 48 patients who either received this special monitoring or standard care. The goal was to s…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Poop pills for cancer? trial tests gut transplant to supercharge immune therapy
Disease control CompletedThis study tested whether a 'gut bacteria transplant' could help patients with advanced kidney cancer respond better to immunotherapy drugs. Fifty patients received either a real transplant of healthy gut bacteria from donors or a placebo, alongside their standard cancer treatmen…
Phase: PHASE1, PHASE2 • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Robot surgeons vs. standard keyhole surgery: which is better for adrenal patients?
Disease control CompletedThis study looked back at past surgeries to compare two types of minimally invasive procedures for removing an adrenal gland. It involved 316 patients and aimed to see if robot-assisted surgery is safer, more effective, or worth the extra cost compared to the standard laparoscopi…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Doctors compare new vs. old liver cancer drugs in real patients
Disease control CompletedThis study looked at how well and how safely a newer combination drug treatment (Atezolizumab-Bevacizumab) works for advanced liver cancer in patients who also have liver scarring (cirrhosis), compared to an older type of drug (TKIs). Researchers followed 38 real-world patients t…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Doctors test bubbles to pinpoint heart catheters
Diagnosis CompletedThis study tested a method to check if a central line catheter is in the right spot in the heart. Researchers injected a small, safe bubble solution into the catheter and used an ultrasound on the chest to see how long it took for the bubbles to appear in the heart. They did this…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Apr 01, 2026 14:43 UTC
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Over half of thyroid cancer patients may need second surgery, study reveals
Diagnosis CompletedThis study looked at whether checking lymph nodes during initial thyroid cancer surgery helps doctors decide the right amount of tissue to remove. Researchers examined 110 patients with small, early-stage thyroid cancer who were scheduled for partial thyroid removal. They found t…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Mar 12, 2026 13:51 UTC
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Looking back at spinal pain relief for hysterectomy patients
Symptom relief CompletedThis completed study looked back at medical records to see how well spinal morphine injections worked for pain relief after robotic hysterectomy surgery. Researchers analyzed data from 100 patients who had this procedure. They specifically examined pain scores to understand if th…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Spinal shot vs IV drip: which eases hysterectomy pain better?
Symptom relief CompletedThis study looked back at 670 women who had hysterectomy surgery to compare two pain relief methods. Researchers wanted to see if giving morphine through a spinal injection works better and is safer than giving it through an IV drip during the first two days after surgery. The go…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Mar 19, 2026 14:56 UTC
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Study tests if a helmet is better than a mask for helping people breathe
Knowledge-focused CompletedThis study aimed to understand if a clear plastic helmet is better than a standard facemask for delivering breathing support to patients with severe lung failure. Researchers tested both methods on 20 patients, measuring how hard they had to work to breathe and their comfort leve…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Doctors-in-Training put to the test in heart surgery skill study
Knowledge-focused CompletedThis study aimed to understand how long it takes heart surgery trainees to become skilled at using two special tools during coronary bypass surgery. The tools help surgeons check the quality of the new blood vessel connections (grafts) during the operation. Researchers observed 8…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scanning for clues: can new imaging tech personalize prostate cancer care?
Knowledge-focused CompletedThis study aimed to see if detailed features from a special type of PET scan (PSMA PET/CT) could help predict how aggressive a man's prostate cancer is. Researchers studied 70 men with intermediate or high-risk prostate cancer who were scheduled for surgery. They compared the sca…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Doctors test custom breathing machine settings to protect failing lungs
Knowledge-focused CompletedThis study aimed to find the best way to set up breathing machines for patients with sudden, severe lung failure. Researchers tested if customizing the machine's pressure based on how hard a patient was trying to breathe was better than using standard settings. They compared thes…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Scientists test cannabis drugs on colon in lab, seeking clues for future gut treatments
Knowledge-focused CompletedThis study aimed to understand how drugs that affect the body's natural cannabis-like system (the endocannabinoid system) change how the colon's muscles contract. Researchers tested these drugs on small, healthy pieces of colon tissue taken from 36 patients during their scheduled…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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10-Year heart disease tracking study seeks clues to predict heart attacks and strokes
Knowledge-focused CompletedThis study aimed to understand how atherosclerosis (hardening of the arteries) develops over time in different parts of the body, like the heart, brain, and legs. Researchers followed 320 patients for 10 years, checking for major events like heart attacks and strokes, and using u…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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First-Hand stories: what It's really like to have a membrane sweep
Knowledge-focused CompletedThis study aimed to understand what it feels like for women to undergo a membrane sweep, a common manual procedure used to help start labor. Researchers interviewed about 20 first-time mothers in Italy shortly after they gave birth to hear their personal stories and feelings abou…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:26 UTC