Fondazione Policlinico Universitario Agostino Gemelli Irccs
Clinical trials sponsored by Fondazione Policlinico Universitario Agostino Gemelli Irccs, explained in plain language.
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Finger cuff device may prevent dangerous blood pressure drops in C-Sections
Disease control CompletedThis study tested a non-invasive finger cuff device that continuously monitors blood pressure and predicts dangerous drops during planned C-sections. 102 pregnant women were randomly assigned to either standard blood pressure checks or the new device. The goal was to see if the d…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated May 17, 2026 00:53 UTC
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Poop pills may boost cancer immunotherapy in kidney cancer patients
Disease control CompletedThis study tested whether transferring gut bacteria from people who responded well to immunotherapy could help others with advanced kidney cancer. 50 participants received either a fecal transplant or a placebo alongside their standard immunotherapy. The goal was to see if this a…
Phase: PHASE1, PHASE2 • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Psoriasis patients prefer wynzora cream over foam in new study
Symptom relief CompletedThis study involved 30 adults with mild-to-moderate psoriasis who had previously used Enstilar foam. Researchers asked participants to try Wynzora cream and then report which treatment they preferred. The goal was to see if people liked Wynzora more, and also to check how well th…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 17, 2026 01:00 UTC
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Spinal morphine may offer better pain relief after hysterectomy
Symptom relief CompletedThis study looked at 670 women who had a hysterectomy to see if giving morphine through a spinal injection works better than through an IV for controlling pain. The goal was to find a way to reduce pain and the need for strong painkillers after surgery. Researchers measured pain …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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New training boosts HIV Patients' quality of life
Symptom relief CompletedThis study tested a training program for people living with HIV to help them become more involved in their own care. The program, led by psychologists, aimed to improve emotional, mental, and behavioral engagement with treatment. 75 participants completed the program, and researc…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Robot reveals fall risk secrets in 355 patients
Knowledge-focused CompletedThis study reviewed data from 355 adults aged 20 to 95 who had their fall risk checked using the Hunova robotic platform. The goal was to understand how well the robot measures fall risk and to improve fall prevention programs. The study did not test a new treatment but instead l…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:05 UTC
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Bubble test may help doctors place catheters faster in heart surgery
Knowledge-focused CompletedThis study tested whether a simple bubble test using ultrasound can accurately show where the tip of a central venous catheter is placed in 22 heart surgery patients. Researchers measured the time it took for bubbles to appear in the heart after injecting saline through the cathe…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:04 UTC
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New PET scan analysis could personalize prostate cancer treatment
Knowledge-focused CompletedThis study looked at whether detailed analysis of PET scans (called radiomics) can help predict how aggressive a person's prostate cancer is. Researchers studied 70 men with newly diagnosed, intermediate- or high-risk prostate cancer who were scheduled for surgery. They compared …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:03 UTC
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Helmet or facemask? small study tests better breathing support
Knowledge-focused CompletedThis study looked at whether a helmet or a facemask is better at helping people breathe when their oxygen levels are very low. Twenty adults with acute hypoxemic respiratory failure took part, and each tried both methods to see which one worked better. The goal was to measure how…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:03 UTC
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Real-World study reveals how two liver cancer drugs stack up in patients with cirrhosis
Knowledge-focused CompletedThis study looked at how well two different treatments work in real life for people with advanced liver cancer and cirrhosis. Researchers compared a combination of two drugs (Atezolizumab and Bevacizumab) to a group of similar patients who took a different type of drug (tyrosine …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:02 UTC
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Tiny implants, big solution for missing teeth?
Knowledge-focused CompletedThis study tested narrow dental implants for replacing a single missing tooth in the front of the mouth where bone or space is limited. Seventeen patients received the implants using computer-guided surgery. The goal was to see how much bone was lost around the implant and how we…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:01 UTC
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10-Year study reveals hidden clues about artery disease
Knowledge-focused CompletedThis study looked at 320 people with atherosclerosis (hardening of the arteries) to see how the disease changes over 10 years. Researchers checked genetic, blood, and ultrasound factors to find links to heart attacks, strokes, and leg problems. The goal was to better understand w…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 01:00 UTC
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Spinal shot before robotic surgery may ease pain afterward
Knowledge-focused CompletedThis study looked back at 100 women who had robotic hysterectomy to see if a spinal injection of morphine before surgery helped control pain afterward. Researchers measured pain scores using a simple scale. The goal was to find better ways to manage pain after this type of surger…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 00:59 UTC
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Tailored breathing support may reduce lung injury in respiratory failure
Knowledge-focused CompletedThis study looked at 20 people with moderate-to-severe acute hypoxic respiratory failure to see if personalized breathing support works better than standard methods. Researchers measured how hard patients had to work to breathe and how much air moved in and out. The goal was to f…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 00:53 UTC
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Moms' voices heard: new study reveals real feelings about labor induction procedure
Knowledge-focused CompletedThis study interviewed 20 women about their experience with membrane sweeping, a common method to start labor. The goal was to understand their feelings and perceptions, not to test a treatment. It provides insights for better patient care.
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Brain oxygen levels tracked in surgery blood pressure study
Knowledge-focused CompletedThis study looked at 48 adults having major abdominal surgery to see if preventing low blood pressure helps maintain brain oxygen levels. One group received standard care, while the other used a special monitor to avoid drops in blood pressure. The goal was to learn how blood pre…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Leukemia Patients' hidden threat: fungal infections under the microscope
Knowledge-focused CompletedThis study followed 150 adults with Philadelphia-negative acute lymphoblastic leukemia to see how many developed invasive fungal infections during the first weeks of chemotherapy. Researchers measured infection rates and deaths linked to those infections. The goal was to better u…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC
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Scientists probe cannabis-like brain chemicals to unlock colon secrets
Knowledge-focused CompletedThis study looked at how drugs that interact with the body's endocannabinoid system (similar to cannabis) affect the movement of the colon. Researchers took healthy colon tissue from 36 colorectal cancer patients during surgery and tested these drugs in the lab. The goal was to u…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC
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Heart surgery training: study tracks Residents' learning curve for better bypass outcomes
Knowledge-focused CompletedThis study looked at how many coronary bypass surgeries cardiac surgery residents need to perform to become skilled at using two imaging tools that check the quality of new blood vessel connections during surgery. 80 adult patients having bypass surgery took part. The goal is to …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 08, 2026 12:00 UTC
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Robot or laparoscope: which adrenal surgery is better?
Knowledge-focused CompletedThis study looked back at 316 patients who had minimally-invasive surgery to remove one adrenal gland. It compared the safety and effectiveness of robot-assisted surgery versus standard laparoscopic surgery. The goal was to see which approach leads to fewer complications, shorter…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 07, 2026 18:38 UTC
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Hidden Gut-Brain disorders common in kids with IBD
Knowledge-focused CompletedThis study looked at 220 children with inflammatory bowel disease (IBD) that was under control to see how many also had disorders of gut-brain interaction (DGBIs), like irritable bowel syndrome (IBS). The goal was to compare these rates to healthy children and find any related fa…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 06, 2026 16:01 UTC
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Hidden cancer cells found in neck nodes of small thyroid tumors
Knowledge-focused CompletedThis study looked at 314 patients with small, single thyroid cancers (1-3 cm) that had no signs of spread before surgery. Doctors planned to remove only half the thyroid, but checked lymph nodes during the operation. They found that over half of patients had cancer in those nodes…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:03 UTC