Fondazione Policlinico Universitario Agostino Gemelli Irccs

This study tested whether transplanting gut bacteria from people who responded well to immunotherapy could help others with advanced kidney cancer respond better. Fifty participants received either a fecal transplant or a placebo. The goal was to see if the transplant could slow …

This study looked at how well a special biopsy method called EUS-FNB can diagnose hard-to-reach tumors in the abdomen, such as those near the bile duct or small intestine. Researchers reviewed data from 131 patients who had this procedure over 10 years. The goal was to see if thi…

This study looked at 52 adults with EGPA (a rare inflammatory disease) and severe chronic sinusitis with nasal polyps. They received mepolizumab 300 mg every 4 weeks. The goal was to see if the drug reduces polyp size and improves symptoms like nasal congestion and sense of smell…

This study tested whether remote occupational therapy could help children and teens (ages 7-18) with Dravet syndrome improve their daily living skills and satisfaction. 14 families participated in online sessions where a therapist coached the child or parent. The goal was to see …

This study tested a new monitoring system that predicts when a mother's blood pressure might drop dangerously during a planned C-section. The device uses a finger cuff to continuously measure blood pressure and an algorithm to warn doctors before a drop occurs. Researchers compar…

This study tested a training program for people living with HIV to help them become more active in managing their health. The program was delivered by psychologists and aimed to improve treatment adherence, quality of life, and emotional well-being. 75 participants took part in t…

This study looked at 670 women who had a hysterectomy to see if a spinal injection of morphine works better than morphine given through an IV for controlling pain. The goal was to reduce pain and the need for opioids after surgery. Researchers compared pain scores, side effects, …

This completed study looked at whether giving a spinal painkiller (morphine) before robotic hysterectomy helps reduce pain after surgery. Researchers reviewed records from 100 patients who had the procedure. The main goal was to see if this approach lowers pain scores, which coul…

This study looked at whether people with mild-to-moderate psoriasis prefer using Wynzora cream over Enstilar foam. Thirty adults who had previously used Enstilar foam tried Wynzora cream for four weeks. Researchers used questionnaires to measure preference, treatment satisfaction…

This study looked at data from 355 adults aged 20 to 95 who had their fall risk assessed using the Hunova robotic platform. The goal was to understand how well the platform measures fall risk and to improve fall prevention programs. Falls are a major cause of injury and death in …

This study observed 150 adults with a specific type of leukemia (Ph-negative ALL) to see how many developed serious fungal infections during their first weeks of chemotherapy. Researchers tracked infection rates and deaths linked to these infections. The goal was to better unders…

This completed Italian study looked at how often children with inactive inflammatory bowel disease (IBD) also have disorders of gut-brain interaction (DGBIs), like irritable bowel syndrome. Researchers used the Rome IV questionnaire to compare 220 children with quiescent IBD to h…

This study looked at how safe and effective a combination of two drugs (Atezolizumab and Bevacizumab) is for people with liver cancer and cirrhosis, compared to standard pills (tyrosine kinase inhibitors). Researchers followed 38 patients to see how long they lived and how their …

This study looked at 48 adults having major abdominal surgery to see if closely managing blood pressure helps keep the brain well-oxygenated. One group used a special monitoring system to prevent low blood pressure, while the other group received standard care. The goal was to le…

This study tested narrow dental implants in 17 patients who were missing a single tooth in the front of the mouth and had limited bone space. The goal was to see if these smaller implants could work well without needing more complex surgeries. Researchers measured bone loss aroun…

This study looked at how many coronary artery bypass surgeries a surgical resident needs to perform to become skilled at using two imaging tools: transit-time flowmetry and high-frequency ultrasound. These tools help check the quality of the new blood vessels during surgery. The …

This study tested whether a simple bubble test, seen with an ultrasound on the chest, can quickly tell doctors where the tip of a central line is placed during heart surgery. In 22 patients, doctors injected a saltwater solution and measured how fast bubbles appeared in the heart…

This study looked at whether a helmet or a facemask is better at helping people with acute low-oxygen respiratory failure breathe easier. Twenty adults each tried both devices in a random order, and researchers measured how hard their breathing muscles worked and how well their l…

This study tested whether personalizing noninvasive breathing support based on a patient's inspiratory effort improves breathing mechanics compared to standard CPAP or NIV. Twenty adults with moderate-to-severe acute hypoxic respiratory failure were enrolled. Researchers measured…

This completed study looked at whether special PET scans can predict how aggressive a person's prostate cancer is. Researchers compared scan features with tumor samples from 70 patients who had surgery. The goal was to see if imaging could replace or reduce the need for invasive …

This study interviewed 20 women after childbirth to learn about their experiences with membrane sweeping, a common method to start labor. The goal was to understand their feelings and perceptions, which are often overlooked. The results could help healthcare providers offer bette…

This study followed 320 people with atherosclerosis for 10 years to see how the disease changes over time. Researchers used ultrasound scans and genetic tests to track artery health and predict heart attacks, strokes, and leg problems. The goal was to better understand why athero…

This study looked at how drugs that interact with the endocannabinoid system (the body's natural cannabis-like system) affect the movement of colon muscle. Researchers took healthy tissue from 36 colorectal cancer patients during surgery and tested these drugs in the lab. The goa…

This study looked back at 316 patients who had surgery to remove an adrenal gland. It compared robot-assisted surgery to standard laparoscopic surgery to see which was safer, more effective, and more cost-effective. The goal was to help doctors choose the best approach for patien…

This study looked at 314 patients with small, early-stage papillary thyroid cancer who had surgery to remove half of the thyroid. During the operation, doctors checked nearby lymph nodes for hidden cancer spread. If cancer was found, the rest of the thyroid was removed in the sam…