European Institute Of Oncology

This study is observing how well a new targeted drug called zolbetuximab works when combined with standard chemotherapy for people with advanced stomach or gastroesophageal junction cancer that has spread. It aims to confirm the drug's effectiveness and safety in real-world patie…

This study is testing whether combining three drugs—atezolizumab, vinorelbine, and cyclophosphamide—can help control advanced triple-negative breast cancer in patients who have already received immunotherapy. The trial aims to see if this combination can shrink tumors and extend …

This study is testing whether freezing small, early-stage breast tumors is as effective as surgery. It's for women aged 50+ with specific low-risk cancers. The goal is to see if this less invasive procedure leads to better quality of life and cosmetic results while still controll…

This study is testing whether a less invasive lymph node surgery is as effective as the standard, more extensive surgery for women with early-stage, hormone-positive breast cancer that has spread to 1-2 lymph nodes. The goal is to reduce side effects like arm swelling and stiffne…

This study is observing how a new genomic test called HER2DX affects the decisions doctors make for patients with early-stage HER2-positive breast cancer. It will see if the test helps doctors choose the best type and timing of drug therapy with more confidence. The study is not …

This study aims to improve the diagnosis of metastatic breast cancer by comparing different methods of testing for a specific gene mutation called PIK3CA. Researchers will test 100 patients using both a standard tissue biopsy and a less invasive blood test (liquid biopsy) to see …

This study is testing whether a special full-body MRI scan can find breast cancer that has returned or spread to other parts of the body earlier than current methods. It will enroll 145 women with high-risk forms of breast cancer (HER2-positive or Triple Negative) who have finish…

This study is testing whether a less invasive lymph node procedure can safely replace more extensive surgery for certain inflammatory breast cancer patients. Researchers want to see if they can accurately identify the first lymph nodes where cancer might spread in patients who re…

This study is testing a new digital platform designed to help cancer patients, survivors, and their families. It aims to identify their specific mental and emotional needs to improve support. The research involves patients, caregivers, and healthcare professionals to gather feedb…

This study is testing whether a special diet that mimics fasting can help reduce high cholesterol, a common side effect of certain breast cancer medications. It will involve 60 post-menopausal women with early-stage breast cancer who are already taking aromatase inhibitors and ha…

This study is collecting information from 200 women about their sexual well-being after mastectomy and breast reconstruction surgery. Researchers will use surveys to understand how different treatments and personal factors affect sexual health. The goal is to identify women who n…

This study aims to create and test a tool that predicts which patients aged 70 and older with head and neck cancer are most likely to experience severe side effects from curative radiation or chemotherapy. Researchers will analyze patient health data to build a predictive score. …

This study is developing and testing a decision-making tool to help women with early-stage breast cancer choose their treatment options. Researchers will compare how the tool affects communication with doctors and decision-making satisfaction. The study involves 180 participants,…

This study aims to understand if a patient's emotional distress at the start of treatment affects how well their first-line therapy works for metastatic breast cancer. It will observe 1,000 patients receiving standard treatments to see if their emotional state is linked to how lo…

This study looks back at genetic test results from over 1,900 people who were tested for a specific gene (TP53) linked to a high risk of cancer. Researchers want to understand how often this gene mutation is found in people who seek testing and how it affects their health over ti…

This study aims to understand if rare, fast-growing neuroendocrine tumors in the lung, thymus, and pancreas should be treated the same way. Researchers will look back at the medical records of 34 patients to compare how they were diagnosed, treated, and how they fared. The goal i…

This study aims to understand how lung cancer changes as it spreads to other parts of the body. Researchers will analyze tumor samples from 25 patients with non-small cell lung cancer to compare the original tumor with where it has spread. The goal is to identify molecular differ…

This study aims to find markers in the blood that might predict which patients with advanced breast cancer are more likely to experience serious side effects from the drug T-DXd. Researchers will observe 84 patients receiving this standard treatment and collect their blood sample…

This study aims to understand why some early-stage breast cancers return after patients finish treatment with specific drugs called CDK4/6 inhibitors. Researchers will follow 750 patients who have taken these drugs to see who relapses and analyze their medical details. The goal i…