New combo aims to outsmart resistant breast cancer

NCT ID NCT07395336

First seen Feb 10, 2026 · Last updated May 09, 2026 · Updated 11 times

Summary

This phase 2 trial tests a combination of two hormone therapies (elacestrant and exemestane) in 26 people with advanced HR+/HER2- breast cancer whose disease has progressed after initial treatment. The study uses a special PET scan to select participants whose tumors still have active estrogen receptors. The goal is to see if this combination can control the cancer for at least 6 months without the need for chemotherapy.

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Contacts and locations

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Conditions

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