New breast cancer surgery could spare women from unnecessary lymph node removal

NCT ID NCT07278726

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for women with early-stage luminal breast cancer that has spread to 1 or 2 lymph nodes. Instead of removing many lymph nodes from the armpit, surgeons will remove only the marked suspicious node and the sentinel nodes. If fewer than 3 nodes are positive, full lymph node removal is avoided, which may reduce side effects like arm swelling. The study aims to see if this targeted approach is safe and effective.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALND are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AO San Giovanni Addolorata

    NOT_YET_RECRUITING

    Roma, Italy, 00184, Italy

  • ASST Sette Laghi - Ospedale di Circolo e Fondazione Macchi

    NOT_YET_RECRUITING

    Varese, Italy, 21100, Italy

  • AUSL Romagna - Presidio Ospedaliero Morgagni-Pierantoni

    RECRUITING

    Forlì, Italy, 47121, Italy

  • Azienda Ospedaliera Universitaria Federico II

    NOT_YET_RECRUITING

    Naples, Italy, 80131, Italy

  • Azienda Ospedaliera Universitaria Pisana

    NOT_YET_RECRUITING

    Pisa, Italy, 56100, Italy

  • Azienda sanitaria universitaria Giuliano Isontina

    NOT_YET_RECRUITING

    Trieste, Italy, 34148, Italy

  • Ente Ospedaliero Cantonale

    NOT_YET_RECRUITING

    Lugano, Switzerland, CH-6500, Switzerland

  • European Institute of Oncology

    RECRUITING

    Milan, Italy, 20141, Italy

  • Fondazione IRCCS Istituto Nazionale Tumori di Milano

    NOT_YET_RECRUITING

    Milan, Italy, 20133, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, Italy, 00136, Italy

  • IRCCS AOU di Bologna - Policlinico di Sant'Orsola

    NOT_YET_RECRUITING

    Bologna, Italy, 40138, Italy

  • IRCCS Humanitas Research Hospital

    RECRUITING

    Rozzano, Italy, 20089, Italy

  • Policlinico San Matteo

    RECRUITING

    Pavia, Italy, 27100, Italy

  • Presidio Ospedaliero "G. Bernabeo"

    NOT_YET_RECRUITING

    Ortona, Italy, 66026, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.