New breast cancer surgery could spare women from unnecessary lymph node removal

NCT ID NCT07278726

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for women with early-stage luminal breast cancer that has spread to 1 or 2 lymph nodes. Instead of removing many lymph nodes from the armpit, surgeons will remove only the marked suspicious node and the sentinel nodes. If fewer than 3 nodes are positive, full lymph node removal is avoided, which may reduce side effects like arm swelling. The study aims to see if this targeted approach is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast tumor luminal A or B hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AO San Giovanni Addolorata

    NOT_YET_RECRUITING

    Roma, Italy, 00184, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • ASST Sette Laghi - Ospedale di Circolo e Fondazione Macchi

    NOT_YET_RECRUITING

    Varese, Italy, 21100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • AUSL Romagna - Presidio Ospedaliero Morgagni-Pierantoni

    RECRUITING

    Forlì, Italy, 47121, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Universitaria Federico II

    NOT_YET_RECRUITING

    Naples, Italy, 80131, Italy

    Contact Phone: •••-•••-••••

  • Azienda Ospedaliera Universitaria Pisana

    NOT_YET_RECRUITING

    Pisa, Italy, 56100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda sanitaria universitaria Giuliano Isontina

    NOT_YET_RECRUITING

    Trieste, Italy, 34148, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ente Ospedaliero Cantonale

    NOT_YET_RECRUITING

    Lugano, Switzerland, CH-6500, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • European Institute of Oncology

    RECRUITING

    Milan, Italy, 20141, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fondazione IRCCS Istituto Nazionale Tumori di Milano

    NOT_YET_RECRUITING

    Milan, Italy, 20133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, Italy, 00136, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IRCCS AOU di Bologna - Policlinico di Sant'Orsola

    NOT_YET_RECRUITING

    Bologna, Italy, 40138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IRCCS Humanitas Research Hospital

    RECRUITING

    Rozzano, Italy, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Policlinico San Matteo

    RECRUITING

    Pavia, Italy, 27100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Presidio Ospedaliero "G. Bernabeo"

    NOT_YET_RECRUITING

    Ortona, Italy, 66026, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact