Astellas Pharma Global Development, Inc.

This study is testing a new long-acting injection called PRL-02 for men with advanced prostate cancer that has returned or stopped responding to prior treatment. The main goals are to find a safe and tolerable dose and to see how well the body handles the drug. Men in the study w…

This is the first human study of an experimental drug called ASP1002 for people with advanced solid tumors that have spread. The main goals are to find a safe dose and check for side effects. The study will enroll adults whose cancers have high levels of a protein called claudin-…

This study is testing whether adding a new drug called setidegrasib to standard chemotherapy helps people with advanced pancreatic cancer that has a specific genetic change (KRAS G12D mutation) live longer. About 614 adults whose cancer has spread and cannot be cured by surgery w…

This study is testing an oral pill called roxadustat as a potential new treatment for anemia (low red blood cells) in children and teenagers with chronic kidney disease. The goal is to see if this pill, taken three times a week for up to a year, is a safe and effective alternativ…

This study is testing a new injectable form of a prostate cancer hormone therapy called ASP5541. It aims to see if this injection, given every 12 weeks, works as well or better than the standard daily pill version and if it causes fewer side effects. The trial will enroll about 2…

This study is checking the safety of an existing cancer drug, enfortumab vedotin, specifically for Indian adults with advanced bladder cancer that has spread and has stopped responding to standard treatments. About 100 participants will receive the drug through an IV infusion eve…

This early-phase study is testing the safety and tolerability of gilteritinib, a drug already approved for a type of leukemia, in adults with advanced ALK-positive non-small cell lung cancer (NSCLC) whose cancer has stopped responding to prior ALK inhibitor treatments. About 40 p…

This study aims to collect long-term safety information on the prostate cancer drug enzalutamide. It is open to about 900 men who are already taking the drug in a previous company-sponsored trial and are still benefiting from it. Participants will continue their treatment and be …

This is the first time a new drug called ASP2998 is being tested in people. The main goal is to find a safe dose and see how well people tolerate it, either by itself or combined with standard cancer treatments. The study will enroll adults with advanced solid tumors that have sp…

This early-stage study is testing a new oral drug called ASP1570 in adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe dose and see how well the drug is tolerated, both by itself and when combined with other stand…

This early-stage study is testing a new drug called ASP2138 for people with pancreatic cancer that can be removed by surgery and has a specific protein called CLDN18.2. Participants receive one injection of ASP2138 two weeks before their scheduled surgery, with the goal of helpin…

This early-stage study aims to check the safety and measure how a new drug called ASP5541 moves through the body in Chinese men with advanced prostate cancer. The drug is given as a hip muscle injection alongside standard hormone therapy and prednisone. The main goals are to unde…

This program provides early access to the drug zolbetuximab for people with advanced stomach or gastroesophageal junction cancer who haven't had prior treatment. It's for patients whose cancer tests positive for a specific protein called claudin18.2. Participants receive zolbetux…

This study is testing whether adding a new drug called zolbetuximab to standard immunotherapy and chemotherapy helps people with advanced stomach or gastroesophageal (GEJ) cancer live longer. It is for adults whose cancer has spread, cannot be removed by surgery, and has specific…

This study is testing a new drug called ASP2138 for people with advanced stomach, gastroesophageal junction (GEJ), or pancreatic cancer. The drug works by guiding the body's own immune cells to attack cancer cells that have a specific marker called CLDN18.2. Researchers will test…

This study is testing a medication called fezolinetant to see if it can safely reduce the number and severity of hot flashes in women who are taking hormone therapy for breast cancer. About 540 women with stage 0-3 breast cancer who have at least 7 moderate-to-severe hot flashes …

This early-stage study aims to understand how three common medications (fluconazole, itraconazole, and carbamazepine) affect the body's processing of a new experimental drug called ASP3082. ASP3082 is being developed to target a specific genetic mutation found in some solid tumor…

This study aims to learn how doctors use an approved eye injection (avacincaptad pegol) to treat advanced macular degeneration in real-world clinics. It will observe 1,000 patients who have already decided with their doctor to start this treatment. The main goal is to collect inf…