Astellas Pharma Global Development, Inc.

This early-stage study tested a new drug called ASP2074 in adults with advanced solid tumors that had spread or couldn't be removed by surgery. All participants had already tried all available standard treatments and were no longer benefiting from them. The main goals were to fin…

This was the first study to test a new oral drug called ASP5502 in people. The main goal was to check its safety and how the body processes it. It involved healthy adults and people with primary Sjögren's syndrome, an autoimmune disease that causes severe dryness and fatigue. The…

This was the first-ever study in people of a new type of CAR-T cell therapy called ASP2802 for B-cell lymphoma that has come back or not responded to prior treatments. The main goal was to find a safe dose and understand how the body handles the treatment. The study was terminate…

This was the first study in people to test a new cancer treatment called ASP1012, which is a virus modified in a lab to specifically infect and destroy cancer cells. The main goals were to find a safe dose and check for side effects in adults whose cancer had spread and who had r…

This study tested a new drug called enfortumab vedotin for patients with a type of bladder cancer that hasn't spread into the muscle wall. The drug was delivered directly into the bladder through a thin tube. The main goals were to find a safe dose and see if it could help contro…

This study tested a new drug, gilteritinib, combined with standard chemotherapy in children and young adults with a specific, aggressive form of acute myeloid leukemia (AML) that had come back or did not respond to initial treatment. The goal was to find a safe and effective dose…