Virus engineered to kill cancer cells tested in first human study
NCT ID NCT06171178
First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 26 times
Summary
This early-phase study tested a lab-modified virus called ASP1012 designed to infect and kill cancer cells while leaving healthy cells alone. It also helps the immune system recognize and attack the cancer. The study included 15 adults with advanced solid tumors who had exhausted standard treatments. Some participants also received the immunotherapy drug pembrolizumab. The trial aimed to find a safe dose and check for side effects, but it was terminated early.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Gabrail Cancer and Research Center
Canton, Ohio, 44718, United States
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Hoag Memorial Hospital Presbyterian
Newport Beach, California, 92663, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Mary Crowley Cancer Research
Dallas, Texas, 75230, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
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The Angeles Clinic and Research Institute
Los Angeles, California, 90025, United States
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University of Iowa Hospitals
Iowa City, Iowa, 52242, United States
Conditions
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