New drug infusion targets tough cancers in early trial
NCT ID NCT07488676
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study tests a new drug called ASP546C in people with advanced stomach, gastroesophageal junction, pancreatic, or certain other solid tumors. The drug is given as an infusion every 3 weeks. The study has two parts: Part 1 finds the best dose in stomach/GEJ cancer patients, and Part 2 tests that dose in pancreatic and other tumor types. The goal is to see if the drug can shrink tumors and to check for side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Duke Cancer Center Durham
RECRUITINGDurham, North Carolina, 27710, United States
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Indiana University (IU) Health - Multi-D Oncology Clinic
RECRUITINGIndianapolis, Indiana, 46202, United States
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National Cancer Center Hospital
RECRUITINGChuo-ku, Tokyo, Japan
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National Cancer Center Hospital East
RECRUITINGKashiwa-shi, Chiba, Japan
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Next Oncology - Austin
RECRUITINGAustin, Texas, 78758, United States
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Next Oncology - Dallas
RECRUITINGIrving, Texas, 75039, United States
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Next Oncology - Houston
RECRUITINGHouston, Texas, 77054, United States
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START Los Angeles
RECRUITINGLos Angeles, California, 90025, United States
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
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START Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
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START New York
RECRUITINGLake Success, New York, 10042, United States
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START San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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The Cancer Institute Hospital of JFCR
RECRUITINGKoto-ku, Tokyo, Japan
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UAB Medicine - UAB Hospital
RECRUITINGBirmingham, Alabama, 35249, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new drug combo shrink Hard-to-Treat tumors?
- Can a pill rouse the immune system against pancreatic cancer?
- A sound wave that could expose hidden pancreatic cancer?
- Can a new immunotherapy combo shrink Hard-to-Treat tumors?