New drug infusion targets tough cancers in early trial

NCT ID NCT07488676

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called ASP546C in people with advanced stomach, gastroesophageal junction, pancreatic, or certain other solid tumors. The drug is given as an infusion every 3 weeks. The study has two parts: Part 1 finds the best dose in stomach/GEJ cancer patients, and Part 2 tests that dose in pancreatic and other tumor types. The goal is to see if the drug can shrink tumors and to check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma cholangiocarcinoma colorectal adenocarcinoma gastroesophageal adenocarcinoma gastroesophageal junction adenocarcinoma invasive breast carcinoma non-small cell lung carcinoma ovarian mucinous adenocarcinoma pancreatic adenocarcinoma small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke Cancer Center Durham

    RECRUITING

    Durham, North Carolina, 27710, United States

  • National Cancer Center Hospital

    RECRUITING

    Chuo-ku, Tokyo, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa-shi, Chiba, Japan

  • Next Oncology - Austin

    RECRUITING

    Austin, Texas, 78758, United States

  • Next Oncology - Dallas

    RECRUITING

    Irving, Texas, 75039, United States

  • Next Oncology - Houston

    RECRUITING

    Houston, Texas, 77054, United States

  • START Los Angeles

    RECRUITING

    Los Angeles, California, 90025, United States

  • START Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

  • START New York

    RECRUITING

    Lake Success, New York, 10042, United States

  • START San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Koto-ku, Tokyo, Japan