New drug targets TROP2 protein in Hard-to-Treat cancers
NCT ID NCT07287995
First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 25 times
Summary
This early-stage study tests a new drug called ASP2998, which targets a protein (TROP2) found on many solid tumors. The drug is given alone or with standard treatments like pembrolizumab or carboplatin. About 428 adults with advanced bladder, lung, stomach, or breast cancers that have not responded to prior therapy will participate. The main goals are to check safety and find the best dose.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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John Theurer Cancer Center at Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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National Cancer Center Hospital
RECRUITINGChuo-ku, Tokyo, Japan
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National Cancer Center Hospital East
RECRUITINGKashiwa-shi, Chiba, Japan
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START New York Long Island
RECRUITINGNew Hyde Park, New York, 11042, United States
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Tennessee Oncology
RECRUITINGNashville, Tennessee, 37203, United States
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The Cancer Institute Hospital of JFCR
RECRUITINGKoto-ku, Tokyo, Japan
Conditions
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