New drug targets tumor protein in first human tests
NCT ID NCT07287995
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new drug, ASP2998, that targets a protein called TROP2 found on many solid tumors. The drug is given alone or with standard treatments like pembrolizumab or carboplatin. The main goals are to check safety and find the right dose. About 428 adults with advanced bladder, lung, stomach, or breast cancers that have not responded to prior therapy may join.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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John Theurer Cancer Center at Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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National Cancer Center Hospital
RECRUITINGChuo-ku, Tokyo, Japan
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National Cancer Center Hospital East
RECRUITINGKashiwa-shi, Chiba, Japan
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START New York Long Island
RECRUITINGNew Hyde Park, New York, 11042, United States
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Tennessee Oncology
RECRUITINGNashville, Tennessee, 37203, United States
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The Cancer Institute Hospital of JFCR
RECRUITINGKoto-ku, Tokyo, Japan