New cancer drug interaction study recruits healthy volunteers
NCT ID NCT07395024
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how three common medicines—fluconazole, itraconazole, and carbamazepine—change the way the body processes a new experimental drug called ASP3082. ASP3082 is being developed for cancers with a specific KRAS mutation. The trial involves 54 healthy adults split into three groups, each receiving ASP3082 alone and then with one of the other drugs. The main goal is to measure drug levels in the blood and check for side effects, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Setidegrasib (ASP3082) given intravenously, plus oral fluconazole, itraconazole, or carbamazepine
What this could lead to
If successful, this study will show how other drugs affect ASP3082 levels in the body, helping guide safe dosing for future cancer trials.
What could go wrong
This is a very early phase 1 study in healthy volunteers, not patients. It only measures drug levels and safety, not whether ASP3082 works against cancer.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Parexel
RECRUITINGBaltimore, Maryland, 21225, United States