New drug combo may help bladder cancer patients keep their bladder

NCT ID NCT07566156

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether two drugs, enfortumab vedotin and pembrolizumab, can control muscle-invasive bladder cancer without needing to remove the bladder. About 390 adults whose cancer hasn't spread outside the bladder will receive either the drug combo or standard chemoradiation. The goal is to see if the combo helps patients live longer and keeps the bladder cancer-free.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign urinary system neoplasm Female Urogenital Diseases infiltrating bladder urothelial carcinoma Male Urogenital Diseases neoplasm Neoplasms by Site transitional cell carcinoma urinary bladder disorder urinary bladder neoplasm Urinary Bladder Neoplasms urinary system disorder Urogenital Diseases Urogenital Neoplasms urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Compass Oncology - West

    RECRUITING

    Tigard, Oregon, 97223, United States

  • Illinois Cancer Specialists

    RECRUITING

    Niles, Illinois, 60714, United States

  • Medical Oncology Hematology Consultants

    RECRUITING

    Newark, Delaware, 19713, United States

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Samsun Clinic - Ridley-Tree Cancer Center

    RECRUITING

    Santa Barbara, California, 93105, United States

  • Texas Oncology

    RECRUITING

    Austin, Texas, 78705, United States

  • Texas Oncology - Northeast Texas

    RECRUITING

    Tyler, Texas, 75702, United States

  • Virginia Oncology Associates

    RECRUITING

    Norfolk, Virginia, 23502, United States

  • Williamette Valley Cancer Institute and Research Center

    RECRUITING

    Eugene, Oregon, 97401, United States