Aarhus University Hospital

This study looks at people whose MRI scans show small areas of brain damage called covert brain infarcts (CBIs), which are linked to a higher risk of future stroke and dementia. Researchers want to see if giving stroke-preventing medications (antiplatelets or statins) can reduce …

This early-phase trial tests two existing drugs, perampanel (used for epilepsy) and senicapoc (previously tested for blood disorders), alone and together, in adults with newly diagnosed glioblastoma. The goal is to see if these drugs are safe and can reach the brain to slow tumor…

This study looks at whether people with an ACL injury can get better with rehabilitation alone, without needing surgery. Researchers will track 400 participants' knee function, symptoms, and how many eventually choose surgery. The goal is to see if a non-surgical approach is a go…

This study tests a treatment called remote ischemic conditioning (RIC) for people who have had a brain aneurysm bleed. RIC involves briefly inflating a blood pressure cuff on the arm to restrict blood flow, which may protect the brain. The study will compare recovery and brain da…

This study tests whether using a special imaging technique called autofluorescence during thyroid cancer surgery can lower the risk of hypoparathyroidism, a condition where the parathyroid glands stop working properly. The trial will involve 160 adults who are scheduled for total…

This study tests whether denosumab, a drug used for osteoporosis, can also improve muscle strength and insulin sensitivity in postmenopausal women with type 2 diabetes. About 40 women will receive either denosumab or a placebo for 12 months. The goal is to see if the drug offers …

This study looks at whether removing part of the parathyroid gland can improve bone density, physical function, and quality of life in kidney transplant recipients who still have high calcium or low phosphate levels. About 85 adults who had a kidney transplant at least 6 months a…

This study tests if cabergoline, a drug used for other conditions, can prevent episodic migraines in adults who have 4 to 14 migraine days per month. Participants will take a weekly pill (either 0.5 mg, 1.0 mg, or a placebo) for 12 weeks, then all will receive cabergoline for ano…

This study tests whether using a special blanket for 4 weeks can improve sleep in 672 young people aged 16-24 who have trouble sleeping. Participants are split into three groups: two get different blankets, and one gets no blanket for comparison. The goal is to find a safe, drug-…

This study uses data from about 475 children with acute lymphoblastic leukemia (ALL) who received the drug Erwinase. Researchers will build a computer model to understand how the drug moves through the body, with the goal of finding the best dose to kill cancer cells while avoidi…

This study tests if using better tools—like chest X-rays with computer help and multiple sample types—can find more tuberculosis cases in clinics in Guinea-Bissau and Ethiopia. About 1,584 adults with TB symptoms will be split into two groups: one gets standard care, the other ge…

This observational study looks at how radiotherapy for anal cancer affects women's vaginal and sexual health. About 80 women who completed chemoradiotherapy 6 to 36 months ago will have a gynecological exam, fill out questionnaires, and allow analysis of their radiation scans. Th…

This study follows 20 people with Parkinson's disease who have a brain procedure called focused ultrasound to stop tremors. Researchers want to understand why some people's tremors come back within two years. Participants will have brain scans and regular check-ups to find clues …

This study looks at whether a comprehensive geriatric assessment (CGA) before bladder cancer surgery helps older, frail patients recover better. About 140 patients aged 65 and older with muscle-invasive bladder cancer will receive either standard care or a CGA with tailored inter…

This study is for people with colorectal cancer that has spread to the liver and hasn't responded to other treatments. Researchers want to learn more about how a special type of radiation therapy called SIRT affects these liver tumors. They will collect and analyze biological sam…