Silent brain infarcts: new trial tests aspirin and statins to prevent stroke and dementia
NCT ID NCT07012629
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether common stroke-preventing medications—aspirin, clopidogrel, and statins—can reduce the risk of future stroke, heart attack, and dementia in people who have small, symptomless areas of brain damage called covert brain infarcts (CBIs). These are often found by chance on MRI scans. The trial will enroll about 1,650 participants across Europe and follow them for up to 3 years to see if treatment lowers the chance of major cardiovascular events and dementia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Aspirin, clopidogrel, rosuvastatin, or atorvastatin
What this could lead to
If successful, this could establish a standard treatment to prevent future strokes and dementia in people with silent brain infarcts.
What could go wrong
This is a large phase 3 trial, but the benefit of these medications for silent brain infarcts is unproven. There is a risk of bleeding or other side effects from the drugs.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aalborg Universitetshospital
NOT_YET_RECRUITINGAalborg, 9000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Aarhus Universitetshospital
NOT_YET_RECRUITINGAarhus, 8200, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Aarhus University Hospital
RECRUITINGAarhus, 8200, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Bispebjerg og Frederiksberg Hospital
NOT_YET_RECRUITINGCopenhagen, 2400, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Herlev Hospital
NOT_YET_RECRUITINGHerlev, 2730, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kolding Hospital
NOT_YET_RECRUITINGKolding, 6000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Odense Universitetshospital
NOT_YET_RECRUITINGOdense, 5000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oslo University Hospital
NOT_YET_RECRUITINGOslo, 0450, Norway
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Regionshospitalet Gødstrup
NOT_YET_RECRUITINGHerning, 7400, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rigshospitalet
NOT_YET_RECRUITINGCopenhagen, 2100, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Roskilde Hospital
NOT_YET_RECRUITINGRoskilde, 4000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Skånes Universitetssjukhus
NOT_YET_RECRUITINGLund, 22242, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Medical Center Hamburg-Eppendorf
NOT_YET_RECRUITINGHamburg, 20246, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsspital - Inselspital - University of Bern
NOT_YET_RECRUITINGBern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••