Surgery may boost bone health in kidney transplant patients with stubborn high calcium

NCT ID NCT07415421

Recruiting now Disease control Sponsor: Aarhus University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares parathyroid surgery to standard monitoring in 85 kidney transplant recipients who still have high calcium and parathyroid hormone levels. The goal is to see if surgery improves bone density, physical function, and quality of life over 12 months. Participants are randomly assigned to either have the surgery or continue with regular check-ups and blood tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Subtotal parathyroidectomy (surgery to remove most of the parathyroid glands)
What this could lead to: If surgery proves better than monitoring, it could become a standard option to improve bone health and daily well-being for kidney transplant patients with this condition.
What could go wrong: This is a small pilot trial with only 85 people, so results may not apply to everyone. Surgery carries risks like infection or low calcium levels, and the benefit over conservative care is not yet proven.

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Conditions

The condition(s) this trial relates to.

hyperparathyroidism tertiary hyperparathyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERPARATHYROIDISM KIDNEY TRANSPLANTATION RECIPIENTS

Contacts and locations

Locations

Departement of Nephrology, Aarhus University hospital
RECRUITING

Aarhus, Central Jutland, 8200, Denmark

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