New drug hopes to shield transplanted kidneys from protein damage

NCT ID NCT07356388

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether finerenone can reduce protein in the urine (proteinuria) of people who have had a kidney transplant. Proteinuria is a sign of kidney damage. The study compares finerenone plus standard care to dapagliflozin plus standard care in 54 adult patients. The main goal is to see if finerenone lowers urine protein levels and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Finerenone

What this could lead to

If it works, finerenone could offer a new way to reduce proteinuria and protect kidney function in transplant recipients, potentially delaying further kidney damage.

What could go wrong

This is a small, early-phase trial with only 54 participants. The drug may not outperform the standard treatment, and side effects like high potassium or kidney issues are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease proteinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Changhai Hospital

    Shanghai, Shanghai Municipality, 200082, China