UROTHELIAL CARCINOMA
Clinical trials for UROTHELIAL CARCINOMA explained in plain language.
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Scientists reprogram Patients' own cells to hunt cancer
Disease control CompletedThis early-stage study tested whether a patient's own immune cells could be genetically modified in a lab to recognize and attack cancer cells, then safely given back to the patient. It involved 10 adults with specific types of bladder, skin (melanoma), or head and neck cancers w…
Matched conditions: UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Adaptimmune • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Scientists test multiple drug combos in race to control tough bladder cancers
Disease control CompletedThis study tested several different immunotherapy-based drug combinations for people with advanced bladder cancer that had worsened after standard chemotherapy. It involved 272 participants and was designed to quickly find and stop treatments that didn't work well while advancing…
Matched conditions: UROTHELIAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New drug combo tested before surgery for tough bladder cancers
Disease control CompletedThis study tested whether giving a combination of two drugs (toripalimab and gemcitabine) before bladder removal surgery could help shrink tumors in patients who couldn't receive standard chemotherapy. The trial involved 50 adults with muscle-invasive bladder cancer who were sche…
Matched conditions: UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Henan Cancer Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New combo therapy fights tough bladder cancer
Disease control CompletedThis study tested whether adding the drug lenvatinib to the immunotherapy pembrolizumab works better than pembrolizumab alone for people with advanced bladder cancer who cannot tolerate standard chemotherapy. It involved 505 participants and aimed to see if the combination helped…
Matched conditions: UROTHELIAL CARCINOMA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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New hope for tough bladder cancers: immunotherapy meets chemo
Disease control CompletedThis early-stage study tested whether combining an immunotherapy drug (avelumab) with a chemotherapy drug (docetaxel) is safe and effective for people with advanced bladder cancer that has spread. The trial specifically focused on patients whose cancer didn't respond to standard …
Matched conditions: UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Yousef Zakharia • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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First human trial tests new weapon against multiple cancers
Disease control CompletedThis early-stage study aimed to find a safe and effective dose of a new drug called TPST-1495, given alone or with an existing immunotherapy (pembrolizumab), for people with advanced solid tumors. It enrolled 89 adults with cancers like colorectal, lung, and head and neck cancer …
Matched conditions: UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Tempest Therapeutics • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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Could your gut hold the key to beating cancer?
Knowledge-focused CompletedThis study aimed to understand why only some patients with advanced bladder cancer benefit from immunotherapy. Researchers analyzed stool and blood samples from 40 patients to see if differences in their gut bacteria could predict treatment response. The goal was to gather knowle…
Matched conditions: UROTHELIAL CARCINOMA
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:51 UTC