New combo tackles tough bladder cancer in early trial

NCT ID NCT03575013

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a combination of two drugs—avelumab (an immunotherapy) and docetaxel (a chemotherapy)—in 21 people with advanced bladder cancer that had stopped responding to standard platinum chemotherapy. The main goals were to check safety and see if the combination could shrink tumors. While the treatment may help control the disease, it is not expected to be a cure, and ongoing management would still be needed.

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Conditions

The condition(s) this trial relates to.

transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States