New scan could sharpen bladder cancer staging

NCT ID NCT04018053

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether a new radioactive tracer called 18F-fluciclovine, used with a PET/CT scan, can better determine the extent of muscle invasive bladder cancer before surgery. Sixteen participants with bladder cancer received the tracer and scan before their planned bladder removal. The goal was to see if the scan could more accurately detect cancer spread compared to standard CT or MRI scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
18F-fluciclovine (a radioactive tracer used in PET scans)
What this could lead to
If successful, this could lead to more accurate staging of bladder cancer, helping doctors choose the best treatment and avoid unnecessary surgery.
What could go wrong
This is a very early, small pilot study with only 16 participants. The tracer may not prove more accurate than current methods, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

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