TYPE 1 DIABETES MELLITUS

This small study tested a new tool called InsuLearn that helps people with type 1 diabetes calculate their insulin doses without needing to count carbohydrates. Seven adults on multiple daily injections used the tool for a day and were compared to their usual care. The goal was t…

This study tested whether an enhanced continuous glucose monitor (eCGM) linked to a decision-support system can help older adults (65+) with type 1 diabetes manage their blood sugar. The system automatically uploads glucose, insulin, and activity data to give personalized insulin…

This study tested a visual injection site map to help people with diabetes rotate where they inject insulin. The goal was to reduce lipohypertrophy—lumpy fatty tissue caused by repeated shots in the same spot—and improve blood sugar control. 170 adults on insulin for at least six…

This study tested an artificial pancreas system that learns a person's exercise patterns to prevent low blood sugar (hypoglycemia) during and after moderate exercise. Fifteen adults with type 1 diabetes used the system for about 4 months, comparing it to a standard version. The g…

This early study tested whether transplanting insulin-making islet cells could help people with type 1 diabetes who already had a kidney transplant. Only 3 patients took part, and they stayed on anti-rejection drugs. The goal was to see if the procedure was safe and could reduce …

This study looked at how well the TouchCare Nano automated insulin delivery system works for children and teens with type 1 diabetes in everyday life. Researchers tracked 76 kids aged 6 to 18 over six months to see if the system helped them spend more time with healthy blood suga…

This study tested a mobile app that teaches teenagers with type 1 diabetes how to better manage their condition. 96 teens aged 12-18 were split into two groups: one used the app, the other received standard care. Researchers measured changes in diabetes knowledge, self-confidence…

This study tested an experimental cell therapy called REACT (rilparencel) in 53 adults with type 1 or 2 diabetes and chronic kidney disease. The therapy involves injecting a person's own kidney cells into their kidneys to see if it can slow the loss of kidney function. The goal i…

This phase 2 trial tested whether infusions of PROCHYMAL, a stem cell product, could safely help people recently diagnosed with type 1 diabetes. The study enrolled 63 participants aged 12–35 who had been diagnosed within the past 20 weeks. Researchers measured how well the pancre…

This study looked at 100 adults with type 1 diabetes who had diabetic ketoacidosis, a serious complication. Researchers compared three insulin approaches: one without basal insulin, one with basal insulin, and one with both basal and bolus insulin. The goal was to see which metho…

This early-stage study tested a new treatment called IBC with MAS-1 in 21 adults recently diagnosed with type 1 diabetes. The goal was to see if it is safe and can retrain the immune system to stop attacking the pancreas, potentially helping the body control blood sugar naturally…

This study tested whether adding a community health worker to the diabetes care team helps children with type 1 diabetes. The health worker provided home visits, social support, and help with setting health goals. The study included 84 children and looked at blood sugar control, …

This early-phase study tested whether a new type of immune cell, called a tolerogenic dendritic cell, is safe for people with type 1 diabetes. The cells were made from each patient's own blood and designed to calm the immune system attack on the pancreas. 32 participants received…

This Phase 3 trial tested whether finerenone, a drug already approved for kidney disease in type 2 diabetes, can also slow kidney damage in people with type 1 diabetes. 241 adults with both conditions took either finerenone or a placebo for 6 months, alongside their usual care. R…

This study tested a hybrid closed-loop insulin delivery system (Control-IQ) in 30 adults with type 1 diabetes. The system combines an insulin pump with a continuous glucose monitor that automatically adjusts background insulin. Participants used the system for 52 weeks, and resea…

This study tested a smart cap that attaches to insulin pens to help people with type 1 diabetes track their injections and glucose data. 42 adults used the device or a blinded version for comparison. The goal was to see if it reduces time spent with high blood sugar and improves …

This pilot study tested two computer algorithms designed to automatically control blood sugar levels in people with type 1 diabetes. Five adults who already use an insulin pump and continuous glucose monitor participated. The goal was to see if the systems could keep blood sugar …

This study looked at new markers in blood and urine to detect and predict the severity of drug-associated acute pancreatitis in adults. Researchers compared these markers in 175 patients with drug-induced pancreatitis, other pancreatic diseases, and healthy volunteers. The goal i…

This completed trial tested how accurately the True Vie I3 continuous glucose monitor measures blood sugar levels in 159 adults with type 1 or type 2 diabetes. Participants wore the device while researchers compared its readings to standard lab measurements. The goal was to see i…

This completed study tested whether sending behavioral nudges through Denmark's official electronic letter system could increase flu vaccination among adults aged 18-64 with chronic diseases. Over 300,000 participants were randomly assigned to receive different types of letters o…

This study tested a program called PREP-DC that teaches teens and young adults with type 1 diabetes how to communicate better with their doctors and get ready for adult diabetes care. 52 participants aged 17-23 were split into two groups: one received the program, the other got s…

This study tested a video-based telemedicine program called REDCHiP for parents of young children (ages 2-6) with type 1 diabetes. The program uses education, behavior training, and therapy to reduce parents' fear of hypoglycemia (low blood sugar). 396 families participated, comp…

This study tested two devices—Coolsense (cold) and Buzzy (cold + vibration)—to see if they could reduce pain and fear in children aged 6-12 during insulin injections. 90 kids with type 1 diabetes were split into three groups: one used Coolsense, one used Buzzy, and one received s…

This completed study looked at how well Danish hospitals followed official guidelines for managing blood sugar in people with diabetes who had major, non-cardiac surgery. Researchers reviewed records from over 13,000 patients treated between 2017 and 2023. They focused on whether…

This study checked how well two continuous glucose monitors (Dexcom G6 and FreeStyle Libre) work when oxygen levels are low. Thirty people with type 1 or type 2 diabetes took part. Researchers compared sensor readings to blood tests during controlled low-oxygen conditions to see …

This completed study followed over 1,000 children with newly diagnosed type 1 diabetes and their healthy siblings for up to three years. Researchers collected genetic information, measured diabetes-related antibodies, and asked about environmental exposures. The goal was to build…

This study looks at how type 2 diabetes affects young people aged 12 to 25. Researchers want to see if giving the pancreas a 2-week rest with insulin shots can improve its ability to make insulin. Participants take metformin, follow a diet, and some also get insulin. The study al…

This study tested whether a special heart ultrasound (speckle tracking strain echocardiography) can detect early heart muscle changes in 61 adults with type 1 diabetes, before symptoms appear. Researchers looked for links between these changes and small blood vessel damage (micro…

This completed study surveyed 166 adults with type 1 diabetes to understand what factors influence their choice of hybrid closed-loop (artificial pancreas) systems. Participants included those already using, waiting to start, or considering such technology. The goal was to learn …

This study examined how the menstrual cycle affects blood sugar and insulin needs in 77 women with type 1 diabetes. Using data from continuous glucose monitors and insulin pumps, researchers compared the follicular and luteal phases. The goal is to help women adjust their diabete…

This study tested five different blood glucose meters in 501 adults with type 1 or type 2 diabetes who use insulin. Participants used multiple devices to see how accurate and reliable each meter is in real-world conditions. The goal was to help people with diabetes and their doct…

This study looked at how non-caloric artificial sweeteners (like those in diet drinks) affect body composition, metabolism, and blood sugar control in 21 youth aged 5-17 with type 1 diabetes. Researchers measured body fat and muscle using special scans and tested blood for marker…

This pilot study tested two automated insulin delivery systems (Medtronic 780G and Tandem t:slim X2) in 20 adolescents with type 1 diabetes. Participants ate breakfasts without telling the device how many carbs they were eating. The goal was to see how well each system controlled…

This study looked at 186 pregnant women with type 1 or type 2 diabetes to understand how fats in the blood relate to baby birth weight. Researchers measured blood fats, diet, and placenta genes. The goal is to find new ways to prevent babies from being born too large, which can c…

This completed study followed over 8,600 children from birth to identify environmental factors—like infections or diet—that may trigger type 1 diabetes in those with genetic risk. Researchers tracked the appearance of diabetes-related autoantibodies and the development of the dis…

This study looked at whether counting protein and fat, in addition to carbohydrates, helps control blood sugar after meals in adolescents with type 1 diabetes. Eleven teens using insulin pumps ate standard and high-fat-high-protein meals, and their blood sugar, hormones, and fatt…