TYPE 1 DIABETES MELLITUS
Clinical trials for TYPE 1 DIABETES MELLITUS explained in plain language.
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Can a smartphone app give teens the upper hand against diabetes?
Disease control CompletedThis study tested whether a special mobile app could help teenagers with Type 1 diabetes manage their condition better. Researchers compared 96 teens who used the educational app against teens who received standard medical care. They measured if the app improved the teens' confid…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Deniz Akkaya Balcı • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Robot pancreas put to the test in scotland
Disease control CompletedThis study tested a hybrid closed-loop insulin system for adults with type 1 diabetes in Scotland. The system links an insulin pump with a continuous glucose monitor to automatically adjust background insulin. Researchers wanted to see how well it worked and how acceptable it was…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: NHS Lothian • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Smart app aims to take the guesswork out of diabetes insulin doses
Disease control CompletedThis small study tested if a smartphone app could simplify mealtime insulin dosing for adults with type 1 diabetes. Instead of counting carbs, participants used the app to estimate meals. The goal was to see if this simpler method could help control blood sugar levels as well as …
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New hope to protect kidneys in type 1 diabetes patients
Disease control CompletedThis study tested whether adding the medication finerenone to standard care could better protect kidney function in adults with both chronic kidney disease and type 1 diabetes. Researchers compared finerenone against a placebo (inactive pill) in 241 participants over 6 months of …
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE3 • Sponsor: Bayer • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Could your own cells help save your kidneys?
Disease control CompletedThis study tested whether injections of a patient's own processed kidney cells (called REACT) could safely slow the worsening of kidney function in people with diabetes and chronic kidney disease. It involved 53 participants who received up to two injections into their kidneys an…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE2 • Sponsor: Prokidney • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Stem cell breakthrough trial aims to halt diabetes attack
Disease control CompletedThis study tested whether stem cell injections could protect the body's insulin-producing cells in people recently diagnosed with type 1 diabetes. Researchers gave 63 participants either the stem cell treatment or a placebo to see if it could slow or stop the immune system's atta…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE2 • Sponsor: Mesoblast, Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Experimental vaccine aims to reset immune system in diabetes
Disease control CompletedThis early-stage study tested whether a vaccine called MER3101 could safely help reset the immune system in people with recent-onset type 1 diabetes. The trial involved 21 adults who had been diagnosed within the past two years, comparing different vaccine doses against a placebo…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Smart cap aims to tame blood sugar spikes in diabetes
Disease control CompletedThis study tested whether a smart cap that attaches to insulin pens helps adults with type 1 diabetes better control their blood sugar. The cap automatically records insulin doses and connects to a phone app to track glucose, food, and activity. Researchers compared 42 patients u…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE4 • Sponsor: Fernando Sebastián Valles • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Can your insulin pump handle a surprise snack? study puts two top devices to the test
Disease control CompletedThis study tested two different automated insulin pumps in teenagers with type 1 diabetes to see which one was better at managing blood sugar after eating a meal without warning. Twenty teens tried both the Medtronic 780G and Tandem t:slim X2 pumps, eating different types of surp…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: University of Catania • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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New approach uses community workers to fight diabetes in kids
Disease control CompletedThis study tested whether adding a trained community health worker to a child's diabetes care team could help improve their blood sugar control. It involved 84 children with poorly controlled type 1 diabetes. The community worker provided personalized support for one year, helpin…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Chilling out the sting: can a cold buzz make insulin shots less scary for kids?
Symptom relief CompletedThis study tested two simple devices to see if they could make insulin injections less painful and frightening for children with Type 1 diabetes. Researchers compared a cold-only device and a combined cold-and-vibration device against standard injection care in 90 children aged 6…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Sweetener study probes hidden health effects in diabetic youth
Knowledge-focused CompletedThis study aimed to understand how non-caloric artificial sweeteners might affect the health of young people with type 1 diabetes. Researchers measured body fat, muscle, and blood markers in 21 youth to see if sweetener use was linked to changes in weight, blood sugar control, or…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists track how monthly cycle affects Women's diabetes control
Knowledge-focused CompletedThis study looked at how different phases of the menstrual cycle affect blood sugar control and insulin needs in women with type 1 diabetes. Researchers analyzed anonymous data from 77 women who used continuous glucose monitors and insulin devices. The goal was to understand thes…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: DCB Research AG • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Scientists search for hidden clues to why diabetic moms have bigger babies
Knowledge-focused CompletedThis study aimed to understand why babies born to mothers with diabetes are often larger, even when blood sugar is well-controlled. Researchers followed 186 pregnant women, including those with type 1 or type 2 diabetes and those without, to see if specific fats in the mother's a…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Massive study hunts hidden triggers of childhood diabetes
Knowledge-focused CompletedThis study aimed to discover what in the environment—like viruses, diet, or stress—might trigger type 1 diabetes in children who are genetically at risk. Researchers followed over 8,600 newborns with a family history of diabetes or high-risk genes from infancy, collecting health …
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Beyond carbs: study tests new meal math for teen diabetes
Knowledge-focused CompletedThis study aimed to understand how the protein and fat in a meal, not just carbohydrates, affect blood sugar levels in teenagers with type 1 diabetes. Researchers fed 11 teens different meals and used continuous glucose monitors to track their blood sugar for 6 hours. The goal wa…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC