TUBERCULOSIS

This early-stage study aimed to test the safety of the BCG tuberculosis vaccine in healthy adults. Researchers planned to give some participants the vaccine and then expose all participants to a weakened TB strain six months later to measure immune responses. The study was withdr…

This study is testing two new investigational vaccines designed to protect against tuberculosis (TB). Researchers are evaluating the safety and immune response of different dose levels in healthy adults who have previously received the standard BCG vaccine. The goal is to find a …

This study is testing the safety of a new tuberculosis vaccine called ID93/GLA-SE. Researchers are using a controlled infection model where 48 healthy volunteers are exposed to a weakened, harmless form of TB bacteria through inhalation. The goal is to see if the new vaccine is s…

This large, late-stage study is testing whether a new vaccine can prevent people from getting tuberculosis (TB). It will enroll over 20,000 healthy adolescents and adults, including people living with HIV, to see if the vaccine is safe and effective. Participants will receive two…

This study is testing a new support program to help people with tuberculosis (TB) in Ethiopia stick to their medication and improve how many cases are found. The program combines family support, daily text message reminders, and special training for health workers. Researchers wi…

This study is testing whether a computer program that reads chest X-rays can help find cases of tuberculosis (TB) and COVID-19 more efficiently in communities in Africa. It will involve over 26,000 adults to see if using this artificial intelligence (AI) tool can speed up diagnos…

This study tests two different drug regimens to prevent tuberculosis (TB) in people at high risk. It compares a shorter, daily 1-month treatment to the standard weekly 3-month treatment. The goal is to see if the shorter course is easier for people to complete and just as safe an…

This study is checking if a weekly tuberculosis (TB) prevention treatment is safe and works well for children and teens who are living with HIV. Researchers want to see how this weekly treatment interacts with the modern HIV medications the participants are taking. The goal is to…

This study aims to find the most effective way to screen for hidden (latent) tuberculosis in people living with HIV in Liberia. Researchers are comparing two different skin tests to see which one works better in this setting. The study involves 200 adult participants who are alre…

This study aims to see if giving a TB vaccine booster through an inhaled mist is more effective than the standard skin injection. Researchers will compare immune responses in 36 adults who received the BCG vaccine as children, including a group with type 2 diabetes. The goal is t…