Can talking therapy cut alcohol use and save lives in TB and HIV patients?

NCT ID NCT04230395

Ongoing Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a 4-session behavioral program to reduce alcohol use in 450 people with TB and HIV in India. Unhealthy drinking can worsen TB and HIV outcomes. The program is added to usual care, and researchers will check if it lowers alcohol use and improves health. The goal is to see if this approach is practical and cost-effective in real-world clinics.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: behavioral intervention (motivational enhancement therapy and cognitive behavioral therapy)
What this could lead to: If successful, this could provide an effective way to reduce alcohol use and improve TB and HIV treatment outcomes in India.
What could go wrong: This is a behavioral intervention, not a drug, so results depend on patient participation. The study is also specific to India, so findings may not apply elsewhere.

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Conditions

The condition(s) this trial relates to.

Alcohol Drinking HIV infectious disease tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV TUBERCULOSIS

Contacts and locations

Locations

BJ Government Medical College and Sassoon General Hospital

Pune, Maharashtra, 4110001, India
Dr. D. Y. Patil Medical College

Pune, Maharashtra, 411018, India

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