Blood test aims to unmask hidden TB infections before they turn deadly

NCT ID NCT06751706

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study investigates whether a blood test can detect the bacteria that cause tuberculosis (TB) in people with active TB and their asymptomatic household contacts. Researchers in Uganda will use several methods, including a DNA-based test, to look for TB bacteria in blood samples. The goal is to develop a better way to identify individuals with latent TB who are at highest risk of developing active disease, so they can receive preventive treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a better blood test to identify who is at highest risk of developing active TB, allowing targeted preventive therapy.
What could go wrong: This is a small, early-stage study (60 participants) focused on detection methods, not treatment. The test may not prove accurate enough for widespread use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

latent tuberculosis infection pulmonary tuberculosis tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LATENT TUBERCULOSIS TUBERCULOSIS

Contacts and locations

Locations

Infectious diseases institute, Makarere University

Kampala, P.O. Box 22418, Uganda

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