Could a One-Month TB pill be as good as three? new trial tests shorter prevention

NCT ID NCT05118490

Ongoing Prevention Sponsor: The Aurum Institute NPC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking two TB prevention drugs daily for one month works as well as taking them weekly for three months. It includes 1,000 people with HIV or those living with someone recently diagnosed with TB. The goal is to see which schedule more people complete and how safe and cost-effective each option is.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease HIV Seropositivity latent tuberculosis infection active tuberculosis prevention target tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV SEROPOSITIVITY HOUSEHOLD CONTACT TUBERCULOSIS

Contacts and locations

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Locations

Fundação Aurum (The Aurum Institute Mozambique)

Chokwé, Gaza Province, Mozambique
The Aurum Institute: Gavin J Churchyard Legacy Centre

Klerksdorp, North West, 2571, South Africa
The Byramjee Jeejeebhoy Medical Centre (BJGMC-JHU) CRS

Pune, Maharashtra, 411001, India
Yayasan KNCV - The Persahabatan Hospital, Jakarta

Jakarta, Jaya, 14350, Indonesia