New TB vaccine put to the test in unique aerosol challenge study
NCT ID NCT06670755
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the safety of a new tuberculosis vaccine called ID93/GLA-SE in 48 healthy adults, some of whom have had the standard BCG vaccine before. Researchers will also use an experimental method where a weakened form of TB bacteria is given as an aerosol to see how the immune system responds. The goal is to gather early safety and immune data, not to treat or cure TB.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ID93/GLA-SE vaccine and BCG Danish 1331 vaccine
What this could lead to
If successful, this study could show that the new TB vaccine is safe and help researchers develop better ways to test TB vaccines in humans.
What could go wrong
This is a very early, small safety study with only 48 participants. The aerosol BCG challenge is experimental and not a licensed method, so results may not apply broadly.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre for Clinical Vaccinology and Tropical Medicine
Oxford, Oxfordshire, OX3 7LE, United Kingdom