TUBERCULOSIS

This study tests whether adding extra nursing care—both in the hospital and at home—helps people with tuberculosis (TB) stick with their treatment. About 40 adults recently diagnosed with TB will receive this support. The goal is to see if more patients complete their full course…

This study tests a 9-month, all-oral drug combination (BLMZ) for people with rifampicin-resistant tuberculosis (TB). About 120 participants aged 12 and older will take the pills and be followed for 24 months to see if the infection clears and stays gone. The goal is to find a sho…

This study tests whether adding steroids and a powerful antibiotic combination to standard care can help more people with HIV survive sepsis, a life-threatening infection. About 344 adults in sub-Saharan Africa will receive either standard treatment or the enhanced therapy. The g…

This study tests a newer biopsy method (EBUS-TBMC) against the standard needle approach (EBUS-TBNA) for diagnosing tuberculosis in swollen chest lymph nodes. About 108 adults with suspected TB will have both procedures during one session to see which method finds signs of TB more…

This study tests whether new, easier-to-use diagnostic tests for tuberculosis (TB) can help find more cases in Indonesia. About 40,000 people with TB symptoms will take part. The goal is to see if these tests lead to faster diagnosis and more people getting treated.

This study tests a 28-day daily pill (rifapentine plus isoniazid) to prevent tuberculosis (TB) in children under 13 years old, including those with HIV. About 144 children will join, split into groups based on HIV status, and be followed for 24 weeks. The goal is to find the best…

This study tests whether having health workers visit families at home can help more children under 15 start and finish tuberculosis (TB) preventive treatment. About 1,300 children in southern Ethiopia will take part. The goal is to see if home-based care works better than the usu…

This study looks at how the immune system works in people with lung diseases like asthma, COPD, pneumonia, and tuberculosis. Researchers will analyze a single blood sample to see how certain immune cells change during inflammation and infection. Participants won't receive direct …

This study aims to create a risk score that helps doctors quickly tell which patients with suspected tuberculosis actually need isolation. Researchers will collect data from 686 hospitalized adults to build a model based on symptoms, history, and test results. The goal is to impr…

This study will test a new blood test called PATHFAST TB LAM to see if it can quickly tell if tuberculosis (TB) treatment is working. Researchers will follow 300 adults in Kenya during their 6-month TB treatment, taking regular samples. The goal is to see if changes in a substanc…