New lung biopsy technique could spot TB faster and safer

NCT ID NCT07459569

Not yet recruiting Diagnosis Sponsor: China-Japan Friendship Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a new biopsy method called EBUS-TBMC against the standard needle approach for diagnosing tuberculosis in chest lymph nodes. About 108 adults with suspected TB will undergo both procedures in one session to see which yields better tissue samples. The goal is to improve diagnostic accuracy and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) procedure
What this could lead to: If successful, this could lead to a more accurate and safer way to diagnose tuberculosis in lymph nodes, reducing the need for repeat procedures.
What could go wrong: This is a small, early-stage trial (108 participants) comparing two procedures. The new method may not prove significantly better or could carry higher bleeding risks.

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Conditions

The condition(s) this trial relates to.

lymph node tuberculosis tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MEDIASTINAL AND HILAR LYMPH NODE ENLARGEMENT TUBERCULOSIS

Contacts and locations

Locations

2nd Yinghuadong Street, Beijing, China

Beijing, Beijing Municipality, 100029, China

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