New study aims to close TB prevention gaps for HIV patients

NCT ID NCT05342064

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at better ways to find and prevent tuberculosis (TB) in people living with HIV. Researchers will test a new screening method and offer patients a choice of TB preventive medicines with extra support like text reminders. The goal is to improve TB detection and help more people complete their preventive treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TB preventive therapy (isoniazid or rifapentine) and adherence support (text reminders, phone calls)

What this could lead to

If successful, this could lead to simpler, more effective TB screening and preventive treatment strategies for people with HIV, reducing TB deaths.

What could go wrong

This is an observational and interventional study, not a treatment trial. Results may not apply to all settings, and adherence support may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coinfection HIV infectious disease latent tuberculosis infection tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine Children's Foundation

    Mbabane, Eswatini

  • Baylor College of Medicine Children's Foundation

    Maseru, Lesotho

  • Baylor College of Medicine Children's Foundation

    Lilongwe, Malawi

  • Baylor College of Medicine Children's Foundation

    Mbeya, Tanzania

  • Baylor College of Medicine Children's Foundation

    Kampala, Uganda