TOBACCO USE
Clinical trials for TOBACCO USE explained in plain language.
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New study tests best way to help HIV patients kick the habit
Disease control CompletedThis study tested three different ways to help people living with HIV stop smoking. Over 670 patients from 13 HIV clinics in Hanoi took part. Nurses either referred patients to a quitline, provided counseling, or offered counseling plus nicotine gum. The goal was to see which met…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: New York University • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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E-Cigs tested as harm reduction for older smokers in opioid treatment
Disease control CompletedThis pilot study looked at whether giving e-cigarettes to adults aged 50 and older who are in treatment for opioid use disorder could help them cut down on smoking. The 36 participants were not trying to quit smoking at the start. Researchers measured how many people switched to …
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Heated tobacco may cut harmful chemical exposure for smokers
Disease control CompletedThis study looked at whether adult smokers who switch to heated tobacco products have lower levels of harmful chemicals in their bodies compared to those who keep smoking regular cigarettes. Over 900 healthy smokers aged 22 to 65 took part. Researchers measured various biomarkers…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Altria Client Services LLC • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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E-Cigarettes help smokers kick the habit?
Disease control CompletedThis study looked at whether smokers who want to cut down can switch to a special research e-cigarette and smoke fewer regular cigarettes. Over 12 weeks, researchers tracked how many cigarettes people smoked and if any quit completely. The goal was to see if e-cigarettes are a he…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New program aims to help FDNY firefighters kick the habit for good
Disease control CompletedThis study tested an enhanced tobacco cessation program for retired FDNY firefighters who smoke. The program automatically enrolled participants in counseling, tailored the advice based on their lung scans and breathing tests, and started a quit-smoking medication (varenicline) e…
Matched conditions: TOBACCO USE
Phase: PHASE4 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can a 45-Minute class help teens quit tobacco?
Prevention CompletedThis study tested a 45-minute classroom program called UP2UTobacco for 9th graders. The goal was to help students quit or avoid tobacco and nicotine products, including e-cigarettes. Nearly 600 students took part, and researchers checked if the program led to more teens being tob…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Virginia • Aim: Prevention
Last updated Jun 27, 2026 12:09 UTC
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Digital ads take on vaping: can a scroll change a habit?
Prevention CompletedThis study tested whether anti-vaping and anti-smoking ads on social media can prevent tobacco use in young adults ages 18-24. Researchers randomly assigned 2,800 participants to see different amounts of digital ads and measured their vaping and smoking habits over 30 days. The g…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: George Washington University • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Brain training game may help smokers kick the habit
Symptom relief CompletedThis study tested whether a simple computer task, called the Approach Avoidance Task (AAT), could help smokers quit. The task aims to change automatic, unconscious thoughts that make people want to smoke. 52 daily smokers who wanted to quit took part. Researchers measured changes…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Jasper A. Smits • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New program aims to help lung cancer patients kick the habit
Symptom relief CompletedThis study tested a program to help lung cancer patients stop smoking and avoid starting again. 21 adults with lung cancer who smoked took part. The program included counseling, a web video, and support calls. The goal was to see if the program was easy to use and if patients lik…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Mindfulness may help you kick both smoking and heavy drinking
Symptom relief CompletedThis study tested a mindfulness-based treatment (MBRP) combined with cognitive behavioral therapy to help people reduce alcohol use and quit smoking. 67 adults who smoked and drank heavily participated. The goal was to see if the program was practical and satisfying for patients,…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can a smartphone app help smokers kick the habit?
Symptom relief CompletedThis study tested a mobile app called Support2Quit that uses a psychological technique called cognitive dissonance to help people stop smoking. The study enrolled 437 adult smokers who wanted to quit. Researchers measured how many people stopped smoking and how much they reduced …
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Oregon Research Behavioral Intervention Strategies, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Chatbot coaches youth to kick the habit
Symptom relief CompletedThis study tested whether a chatbot could help young smokers (up to age 25) quit tobacco. Over 150 participants used the chatbot as part of a youth quitline program. Researchers checked how many joined, stayed, and found it useful, and measured quit rates with saliva tests. The g…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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What do you think your neighbors drink? survey seeks answers
Knowledge-focused CompletedThis completed study surveyed over 1,500 adults in Nyakabare Parish, Uganda, to learn how people perceive tobacco and alcohol use in their community. Participants answered questions about how often they think others smoke or drink. The goal was to understand perceived norms, whic…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Pricing pouches: will smokers switch for a lower price?
Knowledge-focused CompletedThis study looked at how the price of nicotine pouches affects whether people choose them over cigarettes. Researchers surveyed over 1,300 tobacco users online to see how much they would use pouches at different price points. The goal was to understand if nicotine pouches could b…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: William Middleton • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Heated tobacco products put to the test against cigarettes and gum
Knowledge-focused CompletedThis study measured how much nicotine gets into the blood and how smokers feel after using heated tobacco products, regular cigarettes, or nicotine gum. Eighty adult smokers took part in a six-day clinic stay where they tried each product. The goal was to understand the appeal an…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Sweet smokes? study tests if sugar boosts cigarette appeal
Knowledge-focused CompletedThis study looked at how the amount of sugar in cigarette tobacco affects how much people enjoy smoking and how addictive the cigarettes seem. Thirty adult smokers tested cigarettes with different sugar levels and answered questionnaires about their experience. The goal was to se…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Heated tobacco vs. cigarettes: which pollutes the air less?
Knowledge-focused CompletedThis study measured harmful chemicals in the air after adults used either a heated tobacco product (ploom) or regular cigarettes in a sealed room. Researchers tracked over 20 pollutants like nicotine, formaldehyde, and benzene. The goal was to see how the two products differ in s…
Matched conditions: TOBACCO USE
Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Study reveals how ads shape opinions on nicotine pouches
Knowledge-focused CompletedThis study looked at how different marketing messages about tobacco-free nicotine pouches affect what people think about them. Over 5,000 participants in the US, including smokers and young non-users, answered survey questions after seeing ads. The goal was to understand how word…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New spanish screening tool could help catch substance abuse early
Knowledge-focused CompletedThis study tested a Spanish-language electronic screening tool called TAPS-ESP to identify tobacco, alcohol, prescription drug, and illicit substance use in primary care. About 1,000 Spanish-speaking adults from a clinic participated. The goal was to see if the tool accurately de…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:15 UTC
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Can a phone study track how cigarette design changes smoking habits?
Knowledge-focused CompletedThis study tested whether a remote, telehealth approach can work to study how cigarette filter ventilation (the tiny holes in the filter) affects smoking behavior and exposure to harmful chemicals. 64 adult smokers participated from home, using their own devices for video visits …
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Gene test could help smokers quit by matching them to the right drug
Knowledge-focused CompletedThis study tested whether a genetic biomarker called the Nicotine Metabolite Ratio (NMR) can help doctors choose the best FDA-approved smoking cessation medication for each person. 82 daily smokers were assigned to varenicline, bupropion, or nicotine patches based on their NMR re…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New nicotine pouches tested for addictiveness against cigarettes
Knowledge-focused CompletedThis completed study looked at whether six new nicotine oral products (pouches in flavors like cool mint and dragon fruit) are less addictive than regular cigarettes. Forty adult smokers tried each product in a controlled clinic setting. Researchers measured how much participants…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: RAI Services Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New support program aims to help moms after preterm birth
Knowledge-focused CompletedThis study tested a program called Care Coordination after Preterm Birth (CCAPB) to see if it helps mothers who had a preterm baby. The program provides extra support with healthcare access and well-being for six months. Researchers measured how acceptable the program was and its…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Simulated tobacco shop reveals how smokers might respond to FDA bans
Knowledge-focused CompletedThis study looked at how adults who smoke cigarettes daily or only some days might react if certain tobacco products were no longer available. Researchers created a pretend online store where participants could shop for cigarettes and other nicotine products under different rules…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Bethany Shorey Fennell • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Eye-Tracking study reveals how cigar warnings grab attention
Knowledge-focused CompletedThis study tested how different warning labels (pictorial vs. text-only) and flavor descriptors (sweet vs. none) on little cigar and cigarillo packages affect people's attention and emotional reactions. Researchers used eye tracking and skin sensors on 90 adult tobacco users. The…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:29 UTC