TOBACCO USE
Clinical trials for TOBACCO USE explained in plain language.
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Can a puff of vapor break a smoking habit?
Disease control CompletedThis study tested whether smokers could reduce or quit regular cigarettes by switching to a specific type of research e-cigarette. Over 12 weeks, 63 adult smokers tried using the e-cigarettes instead, with support and check-ins from researchers. The goal was to see if this switch…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Apr 02, 2026 00:41 UTC
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Mindfulness therapy tested to break two bad habits at once
Disease control CompletedThis study developed and tested a mindfulness-based group program designed to help people quit smoking and reduce heavy alcohol use at the same time. It involved 67 adults in the Tampa Bay area who were motivated to make these changes. Researchers measured whether participants fo…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Blood test could be key to quitting smoking for good
Disease control CompletedThis study tested if a simple blood test could help doctors choose the most effective quit-smoking medication for each person. Researchers enrolled 82 daily smokers and compared standard treatment to a personalized approach based on how fast a person's body breaks down nicotine. …
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New program aims to help lung cancer patients kick smoking habit
Disease control CompletedThis small pilot study tested a program designed to help lung cancer patients quit smoking and prevent relapse. The program combined phone coaching, educational videos, and standard quit-smoking support. Researchers measured whether patients found the program helpful and complete…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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New program aims to help moms after early births
Disease control CompletedThis study tested whether a special support program was helpful and practical for mothers who recently had a preterm baby. The program provided care coordination and motivational coaching to help with stress, depression, follow-up doctor visits, and healthy habits. Researchers en…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Can your phone talk you out of smoking? new app trial says maybe
Disease control CompletedThis study tested a smartphone app called Support2Quit, designed to help people quit smoking by creating mental discomfort with their smoking habits. Researchers compared the app to a simpler version without this specific feature in 437 adult daily smokers who wanted to quit. The…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Oregon Research Behavioral Intervention Strategies, Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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New digital tool aims to spot substance use issues in Spanish-Speaking patients
Diagnosis CompletedThis study tested a Spanish-language digital screening tool designed to help doctors in primary care clinics identify patients who may have problems with tobacco, alcohol, prescription drugs, or other substances. Researchers enrolled 1000 Spanish-speaking adults to see how well t…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Baylor Research Institute • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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New Quit-Smoking strategy tested on heroes to prevent lung cancer
Prevention CompletedThis study tested whether a more proactive approach could help retired firefighters quit smoking and prevent lung cancer. Researchers compared a standard quit-smoking program against an enhanced program that automatically enrolled people and used personalized counseling based on …
Matched conditions: TOBACCO USE
Phase: PHASE4 • Sponsor: Albert Einstein College of Medicine • Aim: Prevention
Last updated Apr 02, 2026 00:40 UTC
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Can social media ads stop young people from vaping?
Prevention CompletedThis study tested whether seeing different amounts of online anti-tobacco ads could change young adults' attitudes and behaviors toward vaping and smoking. Researchers tracked 2,800 people aged 18-24 to see if more exposure to these digital messages led to less tobacco use. The g…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: George Washington University • Aim: Prevention
Last updated Mar 30, 2026 14:31 UTC
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Texting for quitting: can a chatbot help youth kick the habit?
Symptom relief CompletedThis pilot study tested whether a digital chatbot could provide helpful counseling to support young smokers trying to quit. Researchers enrolled 154 young smokers in Hong Kong to see if they would use the chatbot and stick with the program for six months. The goal was to check if…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Apr 02, 2026 00:41 UTC
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Virtual store tests if smokers will ditch cigarettes for pouches
Knowledge-focused CompletedThis study aimed to understand if nicotine pouches could be a good substitute for cigarettes. Researchers recruited over 1300 tobacco users online and had them use a virtual store to see if they would switch to nicotine pouches when cigarette prices changed. The goal was to gathe…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: William Middleton • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Smoke room study tests if new tobacco device pollutes less
Knowledge-focused CompletedThis study measured the air pollution created by a heated tobacco product (Ploom) compared to regular cigarettes. Thirty-two adult smokers used the products inside a special sealed room. Researchers collected air samples to measure dozens of harmful chemicals and particles releas…
Matched conditions: TOBACCO USE
Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists lock smokers in clinic to test new nicotine pouches
Knowledge-focused CompletedThis study aimed to understand how addictive six modern oral nicotine products (like pouches or lozenges) are compared to regular cigarettes and nicotine gum. Forty smokers lived in a clinic for 10 days to try each product while researchers measured their cravings and how much ni…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: RAI Services Company • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Could less sugar in cigarettes make them less addictive?
Knowledge-focused CompletedThis study aimed to understand if the amount of sugar in cigarette tobacco affects how satisfying and addictive the cigarettes are. Thirty adult smokers attended clinic visits to smoke cigarettes with different sugar levels and filled out questionnaires about their experience. Th…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists test how fast new smoking devices deliver nicotine
Knowledge-focused CompletedThis study aimed to understand how the body absorbs nicotine from four different heated tobacco products compared to a person's usual brand of cigarettes and nicotine gum. It involved 80 adult smokers who tried the products in a clinic over six days. Researchers measured nicotine…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists track eyes to see if cigar warnings work
Knowledge-focused CompletedThis study aimed to understand how people notice and emotionally react to health warnings on little cigars and cigarillos. Researchers tracked the eye movements and skin responses of 90 current cigar users as they looked at different package designs. The goal was to gather eviden…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists test if smoking studies can go remote
Knowledge-focused CompletedThis was a small pilot study to see if researchers could run a smoking study completely remotely using video calls and mail-in kits. It tested whether cigarettes with less air flow in the filter change how much people smoke or the levels of harmful chemicals in their body. The ma…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Virtual shopping study tests future tobacco rules
Knowledge-focused CompletedThis study aimed to understand how potential new tobacco regulations might affect the buying habits of adults who smoke. Researchers asked nearly 700 participants who smoke daily or occasionally to use a simulated online tobacco marketplace. They tracked what products people chos…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Bethany Shorey Fennell • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Ads shape opinions on new nicotine pouch risks
Knowledge-focused CompletedThis study aimed to understand how different marketing features for 'tobacco-free' oral nicotine pouches affect what people think about them. Over 5,000 U.S. adults who smoke and young people who don't use nicotine participated by viewing ads and answering surveys. Researchers me…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:52 UTC