Heated tobacco may cut harmful chemical exposure for smokers
NCT ID NCT06179290
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adult smokers who switch to heated tobacco products have lower levels of harmful chemicals in their bodies compared to those who keep smoking regular cigarettes. Over 900 healthy smokers aged 22 to 65 took part. Researchers measured various biomarkers in urine and blood to see if switching reduces exposure to toxins.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Heated tobacco products (Ploom HTP)
- What this could lead to
- If successful, this could show that switching to heated tobacco products reduces exposure to harmful chemicals compared to smoking cigarettes.
- What could go wrong
- This is a completed study measuring biomarkers, not health outcomes. Reduced exposure does not guarantee reduced disease risk. The study was funded by a tobacco company.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alliance for Multispecialty Research, LLC
Lexington, Kentucky, 40509, United States
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Alliance for Multispecialty Research, LLC
Knoxville, Tennessee, 37920, United States
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Celerion Lincoln
Lincoln, Nebraska, 68502, United States
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Dr. Vince Clinical Research, LLC
Overland Park, Kansas, 66212, United States
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Pillar Clinical Research
Bentonville, Arkansas, 72712, United States
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QPS Bio-Kinetic
Springfield, Missouri, 65802, United States
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Spaulding Clinical Research
West Bend, Wisconsin, 53095, United States
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Woodland Research Northwest
Rogers, Arkansas, 72758, United States
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