SUBSTANCE USE DISORDERS

This study tests a community support program designed to help people with tobacco or substance addiction who also face poverty or housing insecurity. The program provides life-skills workshops, peer guidance, and nicotine replacement therapy to see if it improves quality of life …

This study is testing whether having a trained peer supporter helps people with HIV get better care for mental health or substance use problems. About 405 participants at a Johns Hopkins clinic were randomly assigned to either receive this peer support or continue with their usua…

This study is testing if a text message-based screening and referral program helps pregnant and postpartum women attend and stay in treatment for mental health or substance use issues better than the standard in-person screening method. Over 10,000 participants who are pregnant a…

This study is testing a therapy that treats PTSD and substance use problems together in teenagers, instead of separately as is usually done. It compares a new family-based therapy to standard treatment to see which works better at reducing substance use and PTSD symptoms over a y…

This study tests whether using an online patient portal can improve screening for substance use disorders among people living with HIV. Researchers are comparing portal-based screening to usual clinic-based methods to see which approach reaches more patients and leads to better t…

This early-stage study is checking if psilocybin, the active compound in 'magic mushrooms,' is safe and practical to use alongside psychological support for people with methamphetamine addiction. Twelve adults with meth addiction will receive two oral doses of psilocybin under me…

This study is testing a community outreach program to find and treat hepatitis C (HCV) in people who use drugs in four French cities. It uses a 'peer recruitment' method where participants invite others to get screened and receive immediate treatment if needed. The goal is to see…

This study aimed to improve care for people living with HIV who also struggle with mental health or substance use issues. It planned to use patient questionnaires, train clinic staff, and offer telemedicine appointments to make it easier for patients to get the help they need. Th…

This study is testing a combined therapy and support program for mothers who are in treatment for substance use and have a young child (from pregnancy up to age 5). The goal is to improve child safety and well-being, strengthen the parent-child bond, and reduce the risk of the ch…

This study is testing whether a special smartphone app and connection to a support team can help people with HIV who also struggle with substance use. The goal is to help them stay on their medication, keep their virus at undetectable levels, and make it to their doctor appointme…

This study tests two different support strategies to help community hospitals start medication treatment programs for patients with opioid addiction. Researchers will compare a low-intensity approach with a high-intensity approach across 24 hospitals to see which better helps pat…

This study is testing whether a special hospital care team that treats severe infections and substance use disorders at the same time leads to better health. The team provides coordinated medical care and support for addiction during the hospital stay and for four months after di…

This early-stage study aimed to test if a non-invasive brain stimulation technique could help reduce cravings in people being treated for methamphetamine addiction. The plan was to enroll 40 adults already living in a residential treatment program and randomly assign them to rece…

This study is testing whether a telehealth program delivered by video or phone can help people with alcohol use disorder start treatment and reduce their drinking. Researchers are comparing this remote program to standard care to see which approach works better. The goal is to fi…

This study is testing whether a personalized support program can help prevent early deaths in low-income adults. The program provides health navigation, personalized benefits, and compensation for health-related costs to help participants reduce risks from heavy drinking, heart d…

This study is testing whether a brief, 6-session telehealth parenting program called THRIVE can be successfully offered to mothers recovering from substance use disorder through their child's doctor's office. The program aims to help mothers cope with the stress of parenting and …

This study aims to understand how people physically and emotionally react to stressful situations similar to those in emergency departments. Researchers will have 30 participants (20 with methamphetamine use history and 10 healthy adults) perform public speaking and math tasks in…

This study aims to learn which personal factors predict a person's success in group therapy for alcohol use disorder. Researchers will follow 120 patients through treatment and for up to three years afterward to see if factors like other mental health conditions, personality trai…

This study aims to understand how to best implement a digital health app that helps primary care doctors screen for substance use issues and connect patients to treatment. It will enroll 60 participants from Mayo Clinic primary care sites who are at risk for substance use disorde…

This study aimed to see if a type of brainwave training could help improve brain activity and thinking skills in people recovering from cocaine addiction. Researchers planned to measure brain activity and test memory, attention, and reaction times before and after the training se…