New study tests Team-Based approach to curb overdose risk
NCT ID NCT05713695
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to help people with both substance use and mental health disorders: a full team-based program called MISSION that provides counseling, peer support, and community outreach for 6 months, versus just linking them with a peer specialist. Researchers hope the MISSION program will improve treatment engagement, reduce substance use, and boost mental health. The study involves 208 adults referred from a community hub in Worcester.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MISSION program (behavioral intervention combining counseling, peer support, and community outreach)
- What this could lead to
- If successful, this program could offer a proven way to help people with co-occurring substance use and mental health disorders stay engaged in treatment and reduce their risk of overdose.
- What could go wrong
- This is a relatively small study (208 people) and relies on self-reported outcomes, which may not be fully accurate. The program is intensive and may not work for everyone or be easy to scale.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Massachusetts Medical School
Worcester, Massachusetts, 01655, United States
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