New study tests Team-Based approach to curb overdose risk
NCT ID NCT05713695
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to help people with both substance use and mental health disorders: a full team-based program called MISSION that provides counseling, peer support, and community outreach for 6 months, versus just linking them with a peer specialist. Researchers hope the MISSION program will improve treatment engagement, reduce substance use, and boost mental health. The study involves 208 adults referred from a community hub in Worcester.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MISSION program (behavioral intervention combining counseling, peer support, and community outreach)
What this could lead to
If successful, this program could offer a proven way to help people with co-occurring substance use and mental health disorders stay engaged in treatment and reduce their risk of overdose.
What could go wrong
This is a relatively small study (208 people) and relies on self-reported outcomes, which may not be fully accurate. The program is intensive and may not work for everyone or be easy to scale.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Massachusetts Medical School
Worcester, Massachusetts, 01655, United States