Can ketamine help people stop using meth? new trial aims to find out.

NCT ID NCT06496750

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 40 times

Summary

This study tests whether a short course of intravenous ketamine can help adults with moderate to severe methamphetamine use disorder reduce their drug use. 120 participants will receive either ketamine or a placebo (midazolam) over six weeks, and researchers will check urine samples to see if they have more meth-free days. The goal is to find a new treatment option for a condition with few effective therapies.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addiction Institute of Mount Sinai

    TERMINATED

    New York, New York, 10029, United States

  • Alameda Health System

    RECRUITING

    San Leandro, California, 94578, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Interdisciplinary Substance Use and Brain Injury Facility

    COMPLETED

    Albuquerque, New Mexico, 87106, United States

  • Prisma Health

    RECRUITING

    Greenville, South Carolina, 29617, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Southwestern Medical Center

    ACTIVE_NOT_RECRUITING

    Dallas, Texas, 75247, United States

Conditions

Explore the condition pages connected to this study.