SUBSTANCE USE DISORDERS
Clinical trials for SUBSTANCE USE DISORDERS explained in plain language.
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New program aims to keep ex-inmates on track for recovery
Disease control Not yet recruitingThis study tests a program called MISSION-CJ that helps people leaving jail who have both mental health and substance use disorders. The program connects them with peer support and community services to stay in treatment and avoid relapse. Researchers will track how well particip…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Peer support may boost HIV prevention and addiction treatment for young drug users in india
Disease control Not yet recruitingThis pilot study tests whether a peer-led program called Yuva Sath can help young people (ages 18-29) who inject drugs stay engaged in substance use treatment and HIV prevention. The program includes six one-on-one sessions with a peer counselor and weekly text check-ins. Researc…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Rewriting the story: can a talking therapy help people shed self-stigma and reclaim their identity?
Symptom relief Not yet recruitingThis trial tests whether Narrative Enhancement and Cognitive Therapy (NECT), a 12-session group program, can help adults with severe mental health disorders — including substance use disorders — overcome self-stigma and promote personal recovery. About 106 participants receiving …
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Louise Penzenstadler • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Magic mushroom compound tested for tough depression and addiction
Symptom relief Not yet recruitingThis study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with psychotherapy is safe and can reduce depression and substance use in veterans and first responders who haven't responded to standard treatments. Fifty participants will r…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE1, PHASE2 • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Can a sleep pill help smokers kick the habit?
Symptom relief Not yet recruitingThis study tests whether daridorexant, a recently FDA-approved sleep medication, can improve sleep quality and daytime alertness in smokers who struggle with insomnia during quit attempts. About 44 adult smokers who smoke at least 10 cigarettes daily will take the drug or a place…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE4 • Sponsor: Legacy Health System • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Kratom under the microscope: new study aims to uncover its effects and risks
Knowledge-focused Not yet recruitingThis study looks at how kratom affects people who have used opioids in the past. Researchers will compare kratom to another substance and a placebo to see how the body processes it and what effects it has. The goal is to better understand the potential risks and benefits of krato…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE1 • Sponsor: Christopher D. Verrico • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Can a 12-week program help families support recovery? new study aims to find out.
Knowledge-focused Not yet recruitingThis study tests if a 12-week one-on-one support program is easy to complete and acceptable for people supporting a loved one who recently finished substance use treatment. About 18 participants will attend weekly telehealth sessions and complete surveys and interviews. The goal …
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC