SUBSTANCE USE DISORDERS
Clinical trials for SUBSTANCE USE DISORDERS explained in plain language.
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New approach to starting opioid addiction treatment avoids withdrawal
Disease control TerminatedThis study tested a new method for starting buprenorphine (a medication for opioid use disorder) that avoids the usual withdrawal symptoms. Instead of stopping all opioids first, patients started with very low doses of buprenorphine while still taking their regular opioids. The s…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE4 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated May 17, 2026 00:31 UTC
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Study tests smarter HIV prevention for LGBTQ+ people struggling with addiction
Prevention TerminatedThis study aimed to help HIV-negative transgender women and men who have sex with men who also have a substance use disorder stay on PrEP, a daily pill that prevents HIV. Participants received counseling and text support, with extra help for those still struggling. The study was …
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Friends Research Institute, Inc. • Aim: Prevention
Last updated May 17, 2026 00:28 UTC
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Magic mushroom compound studied for meth addiction safety
Symptom relief TerminatedThis early-stage study looked at whether psilocybin, the active ingredient in magic mushrooms, is safe and practical to use alongside behavioral support for people with methamphetamine use disorder. Only 5 participants were enrolled before the study ended early. The main goal was…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC