New approach to starting addiction treatment avoids withdrawal

NCT ID NCT05118204

First seen Nov 01, 2025 · Last updated Jun 09, 2026 · Updated 31 times

Summary

This study tested a new method of starting buprenorphine (a medication for opioid use disorder) that avoids the usual withdrawal symptoms. Participants were adults with opioid misuse and chronic pain who were already taking opioids. The study compared starting with tiny doses of buprenorphine while continuing other opioids versus the standard approach of stopping opioids first. The trial was terminated early with only 23 participants enrolled.

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Contacts and locations

Locations

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

Conditions

Explore the condition pages connected to this study.