Can a Personality-Targeted program keep teens off drugs?

NCT ID NCT04198974

Ongoing Prevention Sponsor: St. Justine's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a school-based program called PreVenture, which uses brief workshops tailored to teens' personality traits to prevent substance use disorders. Over 12,500 students across Canada are taking part. The goal is to see if this approach can delay or reduce drug and alcohol use compared to standard school prevention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PreVenture program (behavioral intervention: personality-targeted cognitive-behavioral workshops)
What this could lead to: If successful, this program could provide an effective, scalable way to prevent substance use disorders and prescription drug misuse in high-risk teenagers.
What could go wrong: This is a large trial, but results are not yet available. The program may not work as well in all schools or communities, and long-term effects are still unknown.

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Conditions

The condition(s) this trial relates to.

Adolescent Behavior Psychological Well-Being substance-related disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT BEHAVIOR ADOLESCENT DEVELOPMENT SUBSTANCE USE DISORDERS

Contacts and locations

Locations

CHU Sainte-Justine Research Center

Montreal, Quebec, H3T 1C5, Canada
Center for Mental Health and Addicitions

Toronto, Ontario, Canada
Dalhousie University

Halifax, Nova Scotia, Canada
University of British Columbia Okanagan Campus

Kelowna, British Columbia, Canada

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