SOLID TUMORS

This is an early safety study for people with advanced lymphoma, myeloma, or certain solid tumors (like kidney cancer and sarcoma) that have come back after standard treatments. Doctors will collect a patient's own immune cells, genetically modify them in a lab to recognize and a…

This study is testing an experimental drug called BMS-986504 for people with advanced solid tumors that have a specific genetic change called an MTAP deletion. The trial will see if the drug works better when given alone or in combination with other cancer drugs. Researchers will…

This early-stage study is testing a new cancer drug called BI 3923948 for the first time in people. It aims to find the highest safe dose when given alone or combined with an immunotherapy drug. The trial is for adults with advanced solid tumors that have spread and are accessibl…

This study is testing a new type of 'theranostic' drug that first acts like a medical dye to locate cancer in the brain and then delivers targeted radiation to treat it. It is for adults with solid tumors, including HER2-positive breast cancer, that have spread to the brain and a…

This early-stage trial aims to test the safety of an experimental drug called ATB-320 in adults with advanced solid tumors that have spread or progressed despite standard treatments. The study will enroll 24 participants to determine the highest safe dose and identify any serious…

This study is testing if a combination of two drugs—lenvatinib (a targeted therapy) and a PD-1 inhibitor (an immunotherapy)—can help control advanced solid tumors that have a specific genetic feature called '11q13 amplification.' It will involve about 60 adults with various advan…

This is the first study in humans testing a new cancer drug called QLS5316. Researchers will give the drug to 300 patients with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check if the drug is safe, determine the right dose, an…

This study aims to see if a drug called romiplostim N01 is safe and effective at raising platelet counts in adults with solid tumors. It focuses on patients whose low platelet counts are caused by treatment regimens that include radiation therapy. The goal is to help manage this …

This study allows cancer patients who benefited from adagrasib treatment in previous trials to continue receiving the medication while researchers monitor long-term safety. The trial focuses on people with advanced solid tumors including lung and colorectal cancers who are alread…

This early-stage study aims to find a safe dose of a new drug, BI 1831169, when given with an existing immunotherapy (an anti-PD1 antibody) to Japanese adults with advanced solid tumors that have spread. The goal is to see how much of the new drug people can tolerate and to check…

This study is testing a new imaging agent called ⁶⁸Ga-B6FA-01 to see if it can take clearer pictures of solid tumors during a PET/CT scan. It aims to improve cancer detection and monitoring by targeting two markers found in and around tumors. The trial will enroll 100 adults with…