PULMONARY HYPERTENSION

This study is testing whether a gas called inhaled nitric oxide can help newborns with a serious birth defect where the diaphragm doesn't form properly, causing lung problems and high blood pressure in the lungs. The research will involve about 40 newborns who need breathing supp…

This study is testing a medical device designed to lower dangerously high blood pressure in the lungs of people with heart failure. Researchers will compare the device procedure to a placebo procedure in 750 participants who are already on the best available heart medications. Th…

This study is checking the long-term safety of an inhaled powder medicine for people who have both lung scarring and high blood pressure in their lungs. It's for people who have already finished a previous related study. The main goal is to see how well people tolerate the medici…

This study is testing if an investigational drug called Telaglenastat, when added to standard care, can help adults with pulmonary hypertension. The goal is to see if it lowers blood pressure in the lungs and improves heart and lung function. About 28 participants with moderate s…

This study aims to see if using an ultrasound machine can safely guide a special catheter into the heart's arteries to diagnose pulmonary hypertension. Researchers want to test if this method, which avoids X-ray radiation, works as well as the standard approach. The study will en…

This study aims to test if artificial intelligence (AI) can accurately detect pulmonary hypertension and other heart diseases. It will involve 1,000 patients getting a routine heart scan. Researchers will use a smart stethoscope to record heart sounds and electrical activity, the…

This study aims to understand why and how heart problems develop in patients receiving stem cell transplants for blood cancers. Researchers will follow 400 transplant patients for one year, using heart scans, blood tests, and health tracking to identify early warning signs of hea…

This study aims to gather detailed information on a rare condition where high blood pressure in the lungs is linked to abnormal blood vessel connections around the liver. Researchers will follow 300 adult patients over time to understand how the disease develops, how patients res…

This study aims to understand what happens to patients who experience a sudden, severe worsening of their pulmonary hypertension, a condition where high blood pressure in the lungs strains the heart. Researchers will track 200 patients across Europe who are hospitalized for this …

This study aims to understand if having obstructive sleep apnea (OSA) increases a person's risk for high blood pressure in the lungs, known as pulmonary hypertension. Researchers will observe 55 adults already diagnosed with sleep apnea, using heart ultrasound scans to measure lu…

This study aims to define the normal, healthy range for a new measurement of how the heart's right chambers work together, using AI-powered 3D ultrasound scans. It will enroll 2,640 healthy adults and people with specific heart and lung conditions to see how this measurement chan…

This study aims to understand how some people with chronic lung diseases develop high blood pressure in their lungs (pulmonary hypertension). Researchers will examine 105 adults who are already scheduled for lung surgery, comparing those with and without this complication. By ana…