PREVENTION

This study tests whether taking a specific probiotic (Lacticaseibacillus rhamnosus CRL1505) every day can reduce or prevent upper respiratory infections like colds and flu in healthy children aged 3 to 12. About 268 kids will be randomly assigned to receive either the probiotic o…

This study tests a tailored program called REMINDER4Care for adults aged 65 and older living in residential or daycare facilities. The program focuses on social and cognitive activities to reduce dementia risk. Researchers will compare the program to usual care in 100 participant…

This study tests if taking short, 5-minute exercise breaks at work can prevent muscle and joint pain in workers. 150 adults will do either strength or stretching exercises every day for 8 weeks. Researchers will measure physical function and pain to see which type of exercise wor…

This study tests whether adding a drug called aprepitant to standard care can prevent nausea and vomiting after surgery in people at high risk. About 260 adults having outpatient surgery will take part. The goal is to see if this extra medication helps them feel better and avoid …

This study aims to increase colorectal cancer screening among African Americans, who face higher risks and lower screening rates. About 1,200 participants aged 45-75 will receive a free at-home test kit, educational materials, and reminders. Some will also see targeted social med…

This study is creating an educational tool to help women and their doctors decide if a hormone-releasing IUD (LNG-IUS) is right for preventing endometrial cancer. The tool will be tested with 270 women, including those at risk and those who have had the cancer. The goal is to mak…

This study tests whether a virtual assistant (a chatbot) can help adults aged 60 and older complete a 12-week home exercise program. Seventy participants will either use the chatbot for guided workouts or attend in-person group classes. The goal is to see if the chatbot improves …

This study tests if Dialectical Behavioral Therapy (DBT), which focuses on emotions and mindfulness, can help teens aged 14-17 with obesity improve their quality of life and manage weight to prevent type 2 diabetes. Participants will be randomly assigned to weekly group sessions …

This study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (painful bladder bleeding) in 266 people receiving stem cell transplants for blood cancers or severe anemia. Participants are randomly assigned to standard…

This study tests whether alpha lipoic acid, a common antioxidant supplement, can prevent or reduce skin irritation caused by radiation therapy in breast cancer patients. Forty women scheduled for radiation will take the supplement and be monitored for skin reactions and inflammat…

This study compares two ways of giving ondansetron (a lozenge you dissolve in your mouth versus an injection into a vein) to prevent shivering in women having a cesarean section. About 90 women will take part. The goal is to find out which method works better and is more comforta…

This study tests whether using special CT scans to monitor plaque buildup in the heart arteries can help prevent major heart problems like heart attacks and strokes. About 3,100 adults with non-obstructive coronary artery disease will be randomly assigned to either a management p…

This study tests whether an AI-powered chatbot can teach African American adults about oral cancer better than a standard educational handout. About 60 participants will use either the chatbot or the handout, then take surveys to measure their knowledge, attitudes, and satisfacti…

This study tests whether data from wearable devices (like a smart ring and watch) and a smartphone app can help identify people with prediabetes—a condition that raises the risk of developing type 2 diabetes. Researchers will enroll 200 adults aged 45 and older who are overweight…