Daily acyclovir may stop herpes Flare-Ups in rheumatic patients

NCT ID NCT07341386

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study tests whether taking acyclovir daily can prevent herpes simplex outbreaks in people with autoimmune rheumatic diseases like lupus or rheumatoid arthritis. 62 participants will receive either acyclovir or a placebo for 12 months and be monitored for 24 months total. The goal is to see if this approach reduces the number of herpes episodes and is safe for long-term use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Reumatology division of Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo 05403-000

    RECRUITING

    São Paulo, São Paulo, 05403-000, Brazil

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