A family therapy could curb early psychosis risk in youth

NCT ID NCT07743645

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This study tests whether a 16-week family-based psychosocial intervention can reduce persistent and distressing psychotic-like experiences in children and young adults who have a family history of schizophrenia spectrum disorders (SSD). Participants and their caregivers will attend weekly sessions to address their top modifiable risk factors. The trial compares outcomes in those with high versus low baseline brain patterns associated with SSD, using questionnaires and cognitive tests to measure changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A 16-week family-based psychosocial intervention targeting modifiable risk factors for schizophrenia spectrum disorders
What this could lead to
If effective, this approach could offer a way to reduce distressing psychotic-like experiences and potentially lower the risk of developing schizophrenia in high-risk youth.
What could go wrong
This is an early-stage trial with a modest size, and the outcome relies on self-reported symptoms. The intervention may not produce lasting benefits or may not work for everyone.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

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