PREVENTION

This study tests whether doing a follow-up CT scan of the heart arteries in people with non-obstructive coronary artery disease can help doctors adjust treatment to better control cholesterol and prevent heart attacks, strokes, or death. About 3,100 participants will be randomly …

This study tests whether an ondansetron lozenge works as well as an IV injection to prevent shivering in women having a cesarean section. About 90 women will receive either the lozenge or the IV before surgery. The goal is to find a simpler, more comfortable way to reduce shiveri…

This study tests a tailored program called REMINDER4Care for adults aged 65 and older living in residential or daycare facilities. The program focuses on social and cognitive activities to reduce dementia risk. Researchers will compare the program's effects on thinking skills, mo…

This study tests whether a virtual assistant (a chatbot) can help adults aged 60 and older complete a 12-week home exercise program. Seventy participants will either use the virtual assistant or join a standard in-person class. The goal is to see if the tech-based approach improv…

This study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (painful bladder inflammation) in 266 patients receiving stem cell transplants. Participants are randomly assigned to receive either standard care or stand…

This study tests whether adding a drug called aprepitant to standard nausea prevention can help high-risk patients avoid vomiting and nausea after outpatient surgery. About 260 adults at high risk for postoperative sickness will take either aprepitant or a placebo before surgery.…

This study aims to create an educational tool that helps women and their doctors make informed choices about using a levonorgestrel-releasing intrauterine system (LNG-IUS) to prevent endometrial cancer. Researchers will survey 270 women, both with and without a history of the dis…

This study tests whether brief, daily exercise breaks at work can prevent muscle and joint problems in workers. 150 participants will do either strength exercises with elastic bands or standard stretching for 5 minutes each day for 8 weeks. Researchers will measure physical funct…

This study tests whether giving free colorectal cancer screening kits (FIT) to African Americans at a DMV office in Omaha can boost screening rates. 1,200 participants aged 45-75 will receive a kit, educational materials, and reminders. Half will also see social media ads. Resear…

This study tests whether taking alpha lipoic acid, a common antioxidant supplement, can prevent or reduce skin irritation caused by radiation therapy in breast cancer patients. Researchers will enroll 40 women with early-stage breast cancer who are scheduled for radiation. The go…

This study tests whether dialectical behavioral therapy (DBT), a type of talk therapy that teaches mindfulness and emotional skills, can help teens with obesity improve their quality of life and manage weight. About 90 teens aged 14-17 who show signs of depression and are at risk…

This study tests whether a daily probiotic supplement (Lacticaseibacillus rhamnosus CRL1505) can prevent upper respiratory infections like colds and flu in healthy children aged 3 to 12. Over 268 kids will take either the probiotic or a placebo for 12 weeks, then be followed for …

This study looks at whether carbon fiber insoles can improve vertical jump and sprint speed in healthy, moderately active men aged 18-30. Participants will perform tests with and without the insoles to compare results. The goal is to gather data on performance, not to treat or cu…

This study compares an AI-powered chatbot to traditional educational handouts for teaching African American adults about oral cancer. Researchers want to see which method helps people learn more about prevention, risk factors, and early signs. The goal is to find better ways to s…

This study tests whether data from a smart ring, smartwatch, and smartphone app can identify people with prediabetes (higher-than-normal blood sugar) compared to healthy individuals. About 200 adults aged 45 and older who are overweight will wear these devices for 4 weeks and log…