Can a simple pill stop Post-Surgery sickness? new trial aims to find out

NCT ID NCT07248280

Recruiting now Prevention Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a drug called aprepitant to standard nausea prevention can help high-risk patients avoid vomiting and nausea after outpatient surgery. About 260 adults at high risk for postoperative sickness will take either aprepitant or a placebo before surgery. The goal is to see if this extra medicine improves comfort at home during the first 48 hours after the procedure.

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NAUSEA AND VOMITING, POSTOPERATIVE PREVENTION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Centre hospitalier de l'Université de Montréal (CHUM)
RECRUITING

Montreal, Quebec, H2X 0A9, Canada

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••