PREECLAMPSIA

This study tests two types of progestin-only birth control pills (drospirenone and norethindrone) to see which one better controls high blood pressure in women who recently had preeclampsia. About 50 participants will take one of the pills for 6 weeks after leaving the hospital a…

This study tests whether a mobile health program—including home blood pressure monitoring and virtual coaching—can help midlife women better control high blood pressure after having had pregnancy complications like preeclampsia. About 50 women will be assigned to either the progr…

This study looks at whether giving blood pressure medicine (enalapril) to women after they have had preeclampsia can help protect their hearts. Researchers will enroll 60 new mothers to see if they are willing to take part and how their blood pressure responds. The goal is to fin…

This study tests whether a quick bedside ultrasound can help doctors decide if new mothers with preeclampsia need a diuretic (water pill) to lower their blood pressure. About 96 postpartum patients will be enrolled. The goal is to see if this approach speeds up blood pressure rec…

This study tests a program that gives pregnant women personalized nutrition and lifestyle advice based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of problems like preterm birth, preeclampsia, and gestational diabetes. About 500 p…

This study tests whether an injection called topefilgrastim can prevent preeclampsia in 100 pregnant women at high risk for the condition. Participants will receive either a low dose, a higher dose, or standard care. The goal is to see if the drug can lower dangerous blood pressu…

This study tests whether taking 2,000 IU of vitamin D daily during pregnancy can prevent preeclampsia, eclampsia, and HELLP syndrome in about 2,000 pregnant women in Uganda. Half the women will receive vitamin D and half a placebo, and researchers will track outcomes up to six we…

This study tests whether mindfulness training, with or without wearable biosensors, can help prevent preeclampsia in pregnant women at moderate to high risk. 90 participants will be randomly assigned to mindfulness plus sensors, mindfulness alone, or standard prenatal care. The m…

This study tests whether taking progesterone as a vaginal suppository early in pregnancy (before 12 weeks) can prevent preeclampsia, a serious condition involving high blood pressure. About 642 low-risk pregnant women will either receive progesterone or standard care. Researchers…

This study tests whether telling doctors when a pregnant person is at high risk for preeclampsia can increase the use of low-dose aspirin, which is known to help prevent the condition. About 1,000 pregnant individuals at elevated risk will take part, and their doctors will either…

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. The program includes stress reduction tools, a website/app, and other resources. Researchers will compare stress levels and birth outcomes between those who recei…

This study looks at whether stretching or aerobic exercises can help women with mild preeclampsia. Sixty first-time pregnant women, ages 20-30, will do one type of exercise for six weeks. Researchers will measure blood pressure and urine protein levels to see which exercise works…

This study checks if a formula called fullPIERS can accurately predict serious health problems in pregnant women with preeclampsia. Researchers will collect medical information from 50 women at Sohag University Hospital to see how well the model works. The goal is to help doctors…

This study looks at whether measuring the collapse of a neck vein with ultrasound can predict dangerous low blood pressure after spinal anesthesia in women with preeclampsia having a C-section. About 96 women will be observed, and their blood pressure will be tracked for 20 minut…

This study looks at a natural chemical called kynurenine in the blood of pregnant women. Some women have chronic kidney disease, which raises their risk of a dangerous pregnancy complication called preeclampsia. Researchers want to see if kynurenine levels differ between women wi…

This study will observe 120 pregnant women with high blood pressure or preeclampsia to see if certain ultrasound scans and blood tests can predict which cases will become severe. The goal is to find better ways to identify women at risk for serious complications for both mother a…

This study looks at 1,300 women with type 1 diabetes who had a pregnancy. Researchers want to see if a high risk of preeclampsia early in pregnancy is linked to heart disease or plaque in arteries years later. No treatment is given; it is an observational study to better understa…

This study looks at whether allied-health professionals (like pharmacists) can help recruit and follow women who had preeclampsia during pregnancy. About 200 participants will take their blood pressure at home and work with a research pharmacist for 12 months. The goal is to see …

This study looks at whether expressing breastmilk during pregnancy (from week 28) is safe for women at high risk of preterm birth. About 250 pregnant women with conditions like preeclampsia or previous early births will be randomly assigned to express milk or not. Researchers wil…

This study aims to understand what causes preeclampsia, a dangerous pregnancy condition. Researchers will compare blood samples from 500 women—including those who had preeclampsia and those who had healthy pregnancies—to find better ways to diagnose and treat it. The goal is to u…